{"id":"W2315977973","doi":"10.1097/pai.0000000000000334","title":"Flat Intraurothelial Neoplasia Exhibiting Diffuse Immunoreactivity for CD44 and Cytokeratin 5 (Urothelial Stem Cell/Basal Cell Markers): A Variant of Intraurothelial Neoplasia Commonly Associated With Muscle-invasive Urothelial Carcinoma","year":2016,"lang":"en","type":"article","venue":"Applied immunohistochemistry & molecular morphology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Urothelium; Cytokeratin; Pathology; CD44; Immunostaining; Carcinoma in situ; Medicine; Dysplasia; Immunohistochemistry; Carcinoma; Biology; Internal medicine; Cell; Urinary bladder","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004144202,0.001106803,0.00159568,0.0001925355,0.0003420685,0.00005842781,0.0004616797,0.000724997,0.0001554862],"category_scores_gemma":[0.0001037653,0.000906013,0.0003553308,0.0002676606,0.0009705627,0.0001261131,0.0002267215,0.0006590692,0.00001609947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005938428,"about_ca_system_score_gemma":0.001161559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003282629,"about_ca_topic_score_gemma":0.000006831969,"domain_scores_codex":[0.9953514,0.0002157649,0.001156985,0.001442137,0.0006175985,0.001216148],"domain_scores_gemma":[0.9965312,0.0007064728,0.000884522,0.001186863,0.0002993416,0.0003916161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0101571,0.0009956205,0.0008412068,0.0003577526,0.0005370516,0.0006345597,0.0005123364,0.000002666148,0.9825197,0.0001036464,0.0002046559,0.003133703],"study_design_scores_gemma":[0.03194656,0.002372768,0.002821334,0.0002484363,0.00106581,0.0005562382,0.0003026374,0.00001596768,0.9595501,0.000126103,0.0001035716,0.0008904772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881619,0.0003813164,0.003398545,0.0002539953,0.0002382466,0.003025725,0.001463935,0.0001442042,0.002932101],"genre_scores_gemma":[0.9958173,0.00006429058,0.001469547,0.0004877849,0.0002359985,0.0009129742,0.0002964096,0.0002950304,0.0004206596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02296961,"threshold_uncertainty_score":0.999339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00662435511451183,"score_gpt":0.2135214213224288,"score_spread":0.2068970662079169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}