{"id":"W2316060747","doi":"10.1136/annrheumdis-2012-eular.133","title":"AB0133 New evidence linking the in vivo implication of 4-hydroxynonenal in osteoarthritis pathogenesis","year":2012,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Biochemical effects in animals","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Medicine; Osteoarthritis; Cartilage; 4-Hydroxynonenal; Pathogenesis; Pathology; In vivo; Lipid peroxidation; Internal medicine; Oxidative stress; Anatomy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005734487,0.0001134271,0.0003241494,0.00006705811,0.00002245749,0.000006341896,0.0002713496,0.0000582526,0.00006817471],"category_scores_gemma":[0.002067025,0.00006769352,0.0001433614,0.0003626326,0.0001392297,0.0001227339,0.0001104859,0.00009528337,0.000005435825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001810952,"about_ca_system_score_gemma":0.0001001113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002161609,"about_ca_topic_score_gemma":0.00001240149,"domain_scores_codex":[0.9986709,0.0001564996,0.0004832933,0.0001241263,0.0003262626,0.0002389568],"domain_scores_gemma":[0.998295,0.0007972801,0.000244432,0.0004976674,0.0000589347,0.000106664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006194556,0.001242841,0.4838093,0.002935529,0.0001092842,0.000002948497,0.002373929,0.0000727244,0.2525015,0.001195209,0.002937609,0.2521996],"study_design_scores_gemma":[0.0006213103,0.0001396641,0.8122171,0.01058872,0.00008927711,0.00001126317,0.0001265638,0.0001556439,0.1742175,0.001676166,0.00004475552,0.0001120797],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790266,0.01753224,0.00001700224,0.00271283,0.00005222221,0.0005144283,0.00001482456,0.00000916569,0.0001207399],"genre_scores_gemma":[0.9984123,0.0009711579,0.0001217954,0.0003696416,0.000044188,0.00003425715,0.000001775433,0.0000121849,0.00003268946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3284077,"threshold_uncertainty_score":0.2760462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05329122617224245,"score_gpt":0.3341171342668131,"score_spread":0.2808259080945706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}