{"id":"W2316086376","doi":"10.1038/sj.onc.1205145","title":"c-Myc initiates illegitimate replication of the ribonucleotide reductase R2 gene","year":2002,"lang":"en","type":"article","venue":"Oncogene","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Biology; Ribonucleotide reductase; Replication factor C; DNA replication factor CDT1; DNA replication; Replication timing; Origin recognition complex; Genetics; Licensing factor; Pre-replication complex; Gene; Control of chromosome duplication; Minichromosome maintenance; Eukaryotic DNA replication; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001581494,0.0001118513,0.0001080071,0.00002058442,0.00006424754,0.000008368354,0.0002609432,0.00008914721,0.0001152118],"category_scores_gemma":[0.0001304936,0.00008979427,0.0001066788,0.0001044619,0.00007343998,0.000003127841,0.000136406,0.00004702438,0.00003423234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001292912,"about_ca_system_score_gemma":0.00002032851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001019021,"about_ca_topic_score_gemma":0.000004502818,"domain_scores_codex":[0.9991094,0.00005525386,0.0002103676,0.0003337988,0.0001272503,0.0001638827],"domain_scores_gemma":[0.9986645,0.000006238363,0.0001401067,0.001057969,0.00008287314,0.000048329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001058522,0.00006233094,0.0001132789,0.00000802451,0.00002623068,0.000001581416,0.00002848172,0.000021333,0.9932508,0.0001333102,0.003416912,0.002927128],"study_design_scores_gemma":[0.00023566,0.00009253991,0.00017436,0.000009394073,0.00002115325,0.00003902354,0.00001774046,0.0001723366,0.9805297,0.0001734822,0.01842849,0.0001061767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991915,0.0007857609,0.0001332176,0.0003522366,0.0001634482,0.0002148496,0.00006421883,0.00002012585,0.006351083],"genre_scores_gemma":[0.9953901,0.0002365182,0.002405658,0.0002992752,0.0001441729,0.00002694631,0.00006353501,0.00002570708,0.001408148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01501158,"threshold_uncertainty_score":0.3661704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01749481070025619,"score_gpt":0.2383193910505877,"score_spread":0.2208245803503315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}