{"id":"W2316158532","doi":"10.4049/jimmunol.1501249","title":"HIV-1–Mediated BAFF Secretion in Macrophages Does Not Require Endosomal TLRs, Type-I IFN, and Nef, but Depends on the Cellular Phenotype Status","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Endosome; Secretion; Phenotype; B-cell activating factor; Cell biology; Macrophage; Human immunodeficiency virus (HIV); Interferon; Immunology; Chemistry; Biology; Virology; In vitro; Gene; Antibody; Genetics; B cell; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001997499,0.0002653277,0.0002229631,0.0001538234,0.0001586783,0.0002385094,0.0001185181,0.0002662709,0.0005215229],"category_scores_gemma":[0.0001311013,0.0001125746,0.0002167238,0.00008897718,0.0002024365,0.0001833883,0.000231487,0.0003234796,0.0003389803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001720278,"about_ca_system_score_gemma":0.0001332601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002880289,"about_ca_topic_score_gemma":0.0004233806,"domain_scores_codex":[0.9998261,0.00004441036,0.00002062679,0.00002508814,0.00003720347,0.00004661628],"domain_scores_gemma":[0.9998523,0.00004102559,0.00002601116,0.00003023832,0.00002532539,0.00002515936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000552797,0.000009633409,0.0002211962,0.00001620082,0.000001582171,0.00004584623,0.00001442478,0.00001017292,0.9992008,0.00003488629,0.000006433853,0.0003836502],"study_design_scores_gemma":[0.000009367212,0.0002342393,0.00616193,0.000008037609,0.000007863812,0.0005596273,0.00004873246,0.0003232548,0.9913778,0.00004532334,0.001220118,0.000003592078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958882,0.001189386,0.001825151,0.00005085101,0.00001394984,0.00002243073,0.0001789106,0.00002086336,0.0008102769],"genre_scores_gemma":[0.9962013,0.0005147714,0.001702318,0.00003301996,0.00001125303,0.00003162485,0.0003940097,0.000009666433,0.001102047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005215229,"threshold_uncertainty_score":0.001744628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009358738798012016,"score_gpt":0.2159961563708973,"score_spread":0.2066374175728853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}