{"id":"W2316178503","doi":"10.1021/jo502499a","title":"Strategies to Control Alkoxy Radical-Initiated Relay Cyclizations for the Synthesis of Oxygenated Tetrahydrofuran Motifs","year":2014,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; University of British Columbia","keywords":"Tetrahydrofuran; Chemistry; Radical; Relay; Alkoxy group; Hydrogen atom; Substrate (aquarium); Combinatorial chemistry; Oxygen atom; Stereochemistry; Photochemistry; Organic chemistry; Molecule","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004770464,0.0006732582,0.0002504517,0.0003147547,0.000201408,0.0003938291,0.0006806831,0.0004829229,0.00195493],"category_scores_gemma":[0.000433145,0.0002611594,0.0003221035,0.000244088,0.0003803456,0.0007621679,0.000409045,0.001376118,0.0007255511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004032837,"about_ca_system_score_gemma":0.0003434452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002669664,"about_ca_topic_score_gemma":0.0006289126,"domain_scores_codex":[0.9997436,0.00004186552,0.0000314507,0.00006426243,0.00005793951,0.0000608595],"domain_scores_gemma":[0.9997901,0.00004151029,0.00007357583,0.00003525803,0.00003392174,0.00002559553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008649081,0.0001248007,0.00008469613,0.000245382,0.00001965609,0.0003271634,0.0001632274,0.0009658751,0.9799743,0.006116351,0.0003258786,0.01156629],"study_design_scores_gemma":[0.00005031799,0.0005167113,0.0001715732,0.00001269256,0.00001624677,0.0003141859,0.00002711789,0.001889739,0.9863377,0.0005463425,0.01009141,0.0000260191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8081117,0.004835829,0.1677107,0.0006977358,0.0003370749,0.0008429457,0.0005842674,0.0008849636,0.01599477],"genre_scores_gemma":[0.938836,0.003509422,0.05156104,0.0001724545,0.00004746889,0.0003258824,0.0004248569,0.0001063865,0.005016502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00195493,"threshold_uncertainty_score":0.006539941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01627356682890372,"score_gpt":0.2678801716695859,"score_spread":0.2516066048406821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}