{"id":"W2316244629","doi":"10.1039/c6gc90039a","title":"The use of auxiliary substances (e.g. solvents, separation agents) should be made unnecessary wherever possible and innocuous when used","year":2016,"lang":"en","type":"article","venue":"Green Chemistry","topic":"Chemical Synthesis and Characterization","field":"Environmental Science","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Reduction (mathematics); Separation (statistics); Biochemical engineering; Chlorinated solvents; Chemistry; Combinatorial chemistry; Process engineering; Computer science; Engineering; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002898802,0.002892678,0.002218251,0.00131423,0.002174551,0.003159486,0.003362841,0.01103039,0.003802611],"category_scores_gemma":[0.007951058,0.001282739,0.002008097,0.0009849741,0.003907599,0.003537333,0.0009277097,0.02163885,0.006003163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001484469,"about_ca_system_score_gemma":0.001358484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001174471,"about_ca_topic_score_gemma":0.003366577,"domain_scores_codex":[0.9971636,0.0003330154,0.0004222394,0.0004411399,0.00142181,0.0002181298],"domain_scores_gemma":[0.989748,0.004464599,0.0008824588,0.0004306458,0.003705309,0.0007691242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009785809,0.00003767448,0.00003029638,0.0007232541,0.000032017,0.000290735,0.00001898919,0.00006226648,0.001393679,0.001127245,0.982891,0.01329495],"study_design_scores_gemma":[0.00002026124,0.00006633187,0.0002392124,0.0001458033,0.00002967391,0.0003809273,0.00001648841,0.00007602151,0.00112005,0.0009928502,0.9968912,0.00002118417],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"commentary","genre_scores_codex":[0.0001082539,0.01503768,0.0003774064,0.02014113,0.9620044,0.00001917198,0.00003991747,0.00005531284,0.002216741],"genre_scores_gemma":[0.002632102,0.02430236,0.001136923,0.07069086,0.874909,0.00004840044,0.00007026886,0.00009469083,0.02611521],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.01103039,"threshold_uncertainty_score":0.01533049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04893370391739774,"score_gpt":0.2533985763279205,"score_spread":0.2044648724105227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}