{"id":"W2316244629","doi":"10.1039/c6gc90039a","title":"The use of auxiliary substances (e.g. solvents, separation agents) should be made unnecessary wherever possible and innocuous when used","year":2016,"lang":"en","type":"article","venue":"Green Chemistry","topic":"Chemical Synthesis and Characterization","field":"Environmental Science","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Reduction (mathematics); Separation (statistics); Biochemical engineering; Chlorinated solvents; Chemistry; Combinatorial chemistry; Process engineering; Computer science; Engineering; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000101258,0.0001163014,0.0001124061,0.000004172568,0.000101302,0.00003741702,0.000173311,0.00009647613,0.0009493134],"category_scores_gemma":[0.00003668086,0.00007043897,0.00003702127,0.00007019864,0.0002086431,0.0003286615,0.0001168002,0.00005575603,0.00001413605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005873656,"about_ca_system_score_gemma":0.000007434129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001665133,"about_ca_topic_score_gemma":0.00005036866,"domain_scores_codex":[0.9990917,0.00002019644,0.000219663,0.0002380628,0.0002590271,0.0001713758],"domain_scores_gemma":[0.9994286,0.0001186227,0.0001342828,0.0002435955,0.000009658964,0.00006519729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002574315,0.00002983706,0.06869496,0.00001848796,0.00001136972,9.726938e-7,0.000100561,0.000001585925,0.9126608,0.000002967519,0.003656852,0.01479585],"study_design_scores_gemma":[0.0002716835,0.000007885058,0.04676874,0.00005057207,0.00001882627,0.000003340932,0.00003030712,0.0001453088,0.9081856,0.0003382891,0.04401455,0.0001649198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971195,0.00006517675,0.00009640095,0.001887228,0.00002237617,0.00008175915,0.00003581722,0.00001759987,0.0006741137],"genre_scores_gemma":[0.9918286,0.000227254,0.0001308792,0.0001269852,0.00004087854,0.00001177261,0.00001807935,0.00001206757,0.007603535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04035769,"threshold_uncertainty_score":0.9999639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04893370391739774,"score_gpt":0.2533985763279205,"score_spread":0.2044648724105227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}