{"id":"W2316320589","doi":"10.1038/sj.bmt.1703727","title":"Evaluation for synergistic suppression of T cell responses to minor histocompatibility antigens by chloroquine in combination with tacrolimus and a rapamycin derivative, SDZ-RAD","year":2002,"lang":"en","type":"article","venue":"Bone Marrow Transplantation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; BC Children's Hospital; University of British Columbia","funders":"","keywords":"Minor histocompatibility antigen; Medicine; Tacrolimus; Histocompatibility; Chloroquine; Immunology; Pharmacology; Calcineurin; Transplantation; Major histocompatibility complex; Antigen; Internal medicine; Human leukocyte antigen; Malaria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007626165,0.0006781388,0.0009872768,0.0005018864,0.0003538332,0.0003734434,0.000596521,0.0004602548,0.001310771],"category_scores_gemma":[0.0005241683,0.0002851689,0.000528758,0.0004261869,0.0006459228,0.0003389209,0.000271916,0.001011839,0.0002951338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002463961,"about_ca_system_score_gemma":0.0007569448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006260345,"about_ca_topic_score_gemma":0.00139068,"domain_scores_codex":[0.9992757,0.0003033721,0.00006841719,0.00008162588,0.0001115009,0.0001594284],"domain_scores_gemma":[0.9993736,0.000237116,0.00009866918,0.00006652116,0.00003733634,0.0001867957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0169195,0.001731274,0.001116517,0.0001590085,0.00008723257,0.0002379856,0.00009259392,0.0007798271,0.9704297,0.0001854956,0.0001817147,0.008079058],"study_design_scores_gemma":[0.0009670419,0.03440159,0.003761837,0.00001152203,0.0002954567,0.0006015794,0.00005770053,0.00114648,0.9572932,0.00005021397,0.001394095,0.00001932965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970683,0.001074244,0.0007590816,0.00006243017,0.00005466928,0.0001009985,0.0001080153,0.00004719889,0.0007250208],"genre_scores_gemma":[0.9975896,0.0005329965,0.001160808,0.00001886936,0.00004446107,0.00007172339,0.0001667499,0.00001534447,0.0003995077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001310771,"threshold_uncertainty_score":0.004384935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01895950664283098,"score_gpt":0.2430204869202847,"score_spread":0.2240609802774537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}