{"id":"W2316418129","doi":"10.1097/iae.0000000000000627","title":"TREAT-AND-EXTEND REGIMENS WITH ANTI-VEGF AGENTS IN RETINAL DISEASES","year":2015,"lang":"en","type":"review","venue":"Retina","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":279,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Allergan; Heidelberg Engineering; Genentech; Alimera Sciences; Regeneron Pharmaceuticals","keywords":"VEGF receptors; Retinal; Medicine; Cancer research; Ophthalmology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000131201,0.0006863493,0.002365405,0.0002682372,0.00005847616,0.00004389962,0.0001353947,0.0002288853,0.000100454],"category_scores_gemma":[0.00008254942,0.0004291753,0.0003596847,0.0004188258,0.000168099,0.00006253437,0.00009330049,0.0003343393,0.0001335677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002995064,"about_ca_system_score_gemma":0.0005165946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006917163,"about_ca_topic_score_gemma":0.000003554896,"domain_scores_codex":[0.9974248,0.0001808576,0.0005280458,0.0008193337,0.0005398699,0.0005070429],"domain_scores_gemma":[0.9982006,0.0000754169,0.000319519,0.0006445061,0.00009576563,0.0006641711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007560345,0.001346398,0.03497006,0.03459794,0.0006622595,0.01228686,0.00007443274,1.352039e-7,1.043642e-7,0.000133258,0.005996335,0.9091762],"study_design_scores_gemma":[0.002237947,0.00110565,0.03261588,0.04186983,0.007426786,0.001240022,0.00003845488,0.000004334977,1.621229e-7,0.00003839905,0.9128802,0.0005423758],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003252407,0.9853672,4.386016e-7,0.00008040119,0.00004368917,0.001404868,0.0001856553,0.00006546225,0.009599826],"genre_scores_gemma":[0.00105482,0.9933459,0.00009982368,0.00003879485,0.0001631039,0.0001508242,0.0007399111,0.0001144459,0.004292385],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9086338,"threshold_uncertainty_score":0.999816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08029983236916323,"score_gpt":0.3895085987267827,"score_spread":0.3092087663576195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}