{"id":"W2316463379","doi":"10.1021/bc5003357","title":"Dual Mode Fluorescent <sup>18</sup>F-PET Tracers: Efficient Modular Synthesis of Rhodamine-[cRGD]<sub>2</sub>-[<sup>18</sup>F]-Organotrifluoroborate, Rapid, and High Yielding One-Step <sup>18</sup>F-Labeling at High Specific Activity, and Correlated <i>in Vivo</i> PET Imaging and <i>ex Vivo</i> Fluorescence","year":2014,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; Genome British Columbia","keywords":"Chemistry; Fluorescence; Yield (engineering); Fluoride; Fluorophore; Radiochemistry; Radiosynthesis; Combinatorial chemistry; In vivo; Inorganic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002146715,0.0004757507,0.0003101743,0.0001424221,0.00008433891,0.0003198491,0.0003902813,0.0005256633,0.0006941344],"category_scores_gemma":[0.0001653843,0.0002458568,0.0002864015,0.0001519679,0.0002700805,0.0003724182,0.0003404887,0.000669966,0.0007244736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003112001,"about_ca_system_score_gemma":0.0002519714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002885759,"about_ca_topic_score_gemma":0.0002884983,"domain_scores_codex":[0.9998872,0.00001104675,0.000007803806,0.000035849,0.0000294114,0.00002871913],"domain_scores_gemma":[0.9999164,0.000009699467,0.00002692321,0.000008989039,0.00001236785,0.00002556654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000354677,0.000007661473,0.00004482627,0.00003555135,0.000003435064,0.00005307745,0.00001572443,0.0001965292,0.9969902,0.0002287209,0.00005107617,0.002337799],"study_design_scores_gemma":[0.00001059504,0.000116221,0.0001798384,0.000002632891,0.000005653544,0.0002898423,0.000005208352,0.0006956412,0.9955099,0.00003449095,0.00314311,0.000006890918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8526251,0.002444802,0.13892,0.0002514455,0.00008692309,0.0003181639,0.0006542467,0.0008739322,0.003825326],"genre_scores_gemma":[0.8783247,0.001589579,0.1127734,0.0001505009,0.0000317163,0.0002550427,0.0007585067,0.0001514769,0.005965007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006941344,"threshold_uncertainty_score":0.002322078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01122435177475991,"score_gpt":0.2141472989952078,"score_spread":0.2029229472204479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}