{"id":"W2316550831","doi":"10.1155/2006/195957","title":"Tweaking Innate Immunity: The Promise of Innate Immunologicals as Anti‐Infectives","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Infectious Diseases and Medical Microbiology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network; Bill and Melinda Gates Foundation","keywords":"Innate immune system; Biology; Pattern recognition receptor; TLR3; Acquired immune system; Immune system; Intrinsic immunity; TLR7; Immunology; TLR9; Innate lymphoid cell; Toll-like receptor; Proinflammatory cytokine; Antimicrobial peptides; Immunity; Chemokine; Microbiology; Inflammation; Antimicrobial; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002147773,0.0005774816,0.000811192,0.0005529085,0.0004015574,0.002327733,0.0008118505,0.001731287,0.00476751],"category_scores_gemma":[0.001821247,0.0002540631,0.0004223881,0.0003201801,0.002645869,0.004481536,0.001513474,0.004388674,0.001994949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008107813,"about_ca_system_score_gemma":0.0008525557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003343156,"about_ca_topic_score_gemma":0.0004828483,"domain_scores_codex":[0.9993256,0.0002111635,0.00003393717,0.00009036715,0.000230048,0.0001088866],"domain_scores_gemma":[0.9989532,0.0005016783,0.00009731489,0.0000803769,0.0001837203,0.0001837037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007111221,0.0002245144,0.0009320508,0.003369204,0.00009705783,0.0005121988,0.0005806916,0.001205338,0.0705517,0.239435,0.06028302,0.622098],"study_design_scores_gemma":[0.00007855632,0.0004735542,0.000547457,0.0006817331,0.00004238915,0.0005906359,0.0002652717,0.001056073,0.01549055,0.09216648,0.8885424,0.00006495248],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.008499518,0.917776,0.01552894,0.03479167,0.008233291,0.00004361583,0.0001283056,0.000297646,0.01470084],"genre_scores_gemma":[0.1237855,0.7999703,0.01723205,0.02282097,0.01088462,0.0001407253,0.0001802846,0.0001378402,0.02484772],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00476751,"threshold_uncertainty_score":0.01594889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00425192866404711,"score_gpt":0.2157059360399584,"score_spread":0.2114540073759113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}