{"id":"W2316641879","doi":"10.1021/bi400951q","title":"Unraveling the Substrate Recognition Mechanism and Specificity of the Unusual Glycosyl Hydrolase Family 29 BT2192 from <i>Bacteroides thetaiotaomicron</i>","year":2014,"lang":"en","type":"article","venue":"Biochemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Saskatchewan","keywords":"Bacteroides thetaiotaomicron; Hydrolase; Glycosyl; Galactoside; Chemistry; Glycoside hydrolase; Stereochemistry; Moiety; Active site; Enzyme; Binding site; Fucose; Biochemistry; Substrate (aquarium); Bacteroides; Biology; Galactose; Genetics; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001494886,0.0002781927,0.0002333762,0.00009477886,0.0001093866,0.0002915749,0.000263395,0.000338271,0.0004600252],"category_scores_gemma":[0.0001726767,0.00008511113,0.000248693,0.0001826774,0.0001391513,0.0003449791,0.0001366444,0.000330342,0.0002578618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002374056,"about_ca_system_score_gemma":0.0001993186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001170914,"about_ca_topic_score_gemma":0.0006965439,"domain_scores_codex":[0.9999369,0.00001488696,0.000004477245,0.00001197205,0.00001798849,0.00001369641],"domain_scores_gemma":[0.9999503,0.000009160917,0.00001250477,0.000005526182,0.00000855813,0.00001387545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001664712,0.00002961638,0.002239986,0.00007950812,0.0000093833,0.0002325114,0.00004395636,0.0006367523,0.9924159,0.000200851,0.00005993517,0.003885153],"study_design_scores_gemma":[0.00005322872,0.0005803439,0.05694933,0.00003485306,0.00006969645,0.003128435,0.0003638341,0.02429092,0.8991652,0.0006858519,0.01463466,0.00004361734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956188,0.001443038,0.002187636,0.00009671765,0.000007499682,0.000009664136,0.000103744,0.00002686219,0.0005061014],"genre_scores_gemma":[0.9963511,0.0006980171,0.002265558,0.00002409491,0.000005021938,0.000004835537,0.0003254352,0.000006279135,0.0003197327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001170914,"threshold_uncertainty_score":0.002328217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01334943908215406,"score_gpt":0.2204527346982854,"score_spread":0.2071032956161313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}