{"id":"W2316679322","doi":"10.1038/sj.gt.3301123","title":"Regulation of T-helper-1 versus T-helper-2 activity and enhancement of tumor immunity by combined DNA-based vaccination and nonviral cytokine gene transfer","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"CTL*; Biology; Immune system; DNA vaccination; Immunity; Carcinoembryonic antigen; Cellular immunity; Antigen; Immunology; Immunization; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003260733,0.0002122374,0.0003888448,0.00009543537,0.0001526907,0.000007731161,0.0001185484,0.0001473611,0.001429103],"category_scores_gemma":[0.000008114406,0.0001944988,0.00007483618,0.0001228864,0.000189698,0.0001197683,0.00001144,0.0001318616,0.000005553129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002896571,"about_ca_system_score_gemma":0.00004987373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001733401,"about_ca_topic_score_gemma":0.000006324636,"domain_scores_codex":[0.9987522,0.0004077283,0.0003436524,0.0002228964,0.00005978562,0.0002137465],"domain_scores_gemma":[0.9993659,0.0001433353,0.0001065658,0.000302553,0.00006731202,0.00001434051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02471527,0.0003993404,0.0001206728,0.0000160075,0.0001975362,1.960912e-7,0.0004557584,0.000005654782,0.8745141,0.0000108345,0.00002562353,0.09953898],"study_design_scores_gemma":[0.01198674,0.002534888,0.04646172,0.00001529103,0.00002874125,0.000005054436,0.00003081888,0.00002479601,0.936814,0.00001602373,0.001910295,0.0001716037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892915,0.009565346,0.0003439306,0.0001354163,0.0001237494,0.0003890444,0.00007489979,0.00002166639,0.00005444765],"genre_scores_gemma":[0.9957519,0.003489536,0.00007837726,0.00005431665,0.000007475286,0.00002335495,0.0001479752,0.00001953063,0.000427587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09936738,"threshold_uncertainty_score":0.9994837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01202781273986617,"score_gpt":0.2332652338821894,"score_spread":0.2212374211423233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}