{"id":"W2316708554","doi":"10.1097/00054725-200912002-00125","title":"Adalimumab Therapy maintains meaningful rates of steroid-free remission in patients with Crohnʼs Disease for up to 3 Years of Therapy: Results From an Open-Label Extension of CHARM","year":2009,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Adalimumab; Medicine; Crohn's disease; Internal medicine; Monoclonal antibody; Open label; Monoclonal; Gastroenterology; Prednisolone; Surgery; Disease; Randomized controlled trial; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00302814,0.0007703523,0.002527847,0.0004588294,0.0006173718,0.0009713725,0.0005710707,0.0008240509,0.001499424],"category_scores_gemma":[0.002187428,0.0003363273,0.001766403,0.000529792,0.0006944686,0.0009466224,0.0005206969,0.002377461,0.0004348114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007915345,"about_ca_system_score_gemma":0.0009073232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007229191,"about_ca_topic_score_gemma":0.001443097,"domain_scores_codex":[0.9984641,0.0007617571,0.0001330729,0.0001888394,0.0002190079,0.0002332447],"domain_scores_gemma":[0.998562,0.0002798528,0.0002711687,0.0002514407,0.0001306799,0.0005047854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7195998,0.05177863,0.01037522,0.0008149121,0.001125906,0.00025215,0.0003831525,0.0004558947,0.01711302,0.0001014176,0.001533091,0.1964668],"study_design_scores_gemma":[0.2310162,0.6831042,0.07428414,0.0001103736,0.0008505341,0.0004363,0.0001067316,0.0008067223,0.00419795,0.0001547455,0.004874969,0.00005712814],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911936,0.006248521,0.0003042131,0.0001644726,0.0001113917,0.0004651633,0.0003058313,0.00005295498,0.00115386],"genre_scores_gemma":[0.9946492,0.001831596,0.0007755149,0.0003861564,0.0002470022,0.000361615,0.0008483706,0.00001558802,0.0008850233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00302814,"threshold_uncertainty_score":0.01601452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01950664054951282,"score_gpt":0.28605515737709,"score_spread":0.2665485168275771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}