{"id":"W2316741177","doi":"10.1038/ncomms10873","title":"GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; NIH Office of the Director; Albert-Ludwigs-Universität Freiburg; University of Texas Southwestern Medical Center; University of Pittsburgh; National Institutes of Health","keywords":"AMPA receptor; Neurotransmission; Neuroscience; Synaptic plasticity; Long-term potentiation; Hippocampal formation; Synaptic fatigue; Silent synapse; Glutamate receptor; Synaptic augmentation; Synaptic cleft; Cell biology; Long-term depression; Chemistry; Biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001301175,0.0004969917,0.0003590166,0.000270105,0.0001658858,0.0002511066,0.0003140419,0.000335494,0.0009926627],"category_scores_gemma":[0.0001314479,0.0001433105,0.0002737191,0.0002249627,0.0003723215,0.0001704079,0.0002014487,0.0006724332,0.0003453325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004232706,"about_ca_system_score_gemma":0.0003075823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008410845,"about_ca_topic_score_gemma":0.00137799,"domain_scores_codex":[0.9998684,0.00002107221,0.00001646661,0.00002038003,0.00003672197,0.00003697604],"domain_scores_gemma":[0.9999166,0.000009246441,0.00002680843,0.00001136071,0.000007759626,0.00002826247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001841685,0.00003755302,0.0001306977,0.00004445829,0.000006360735,0.00005893497,0.00001106197,0.00008397207,0.9980581,0.00008086251,0.00008756172,0.00121635],"study_design_scores_gemma":[0.00007316555,0.0006035335,0.00339948,0.000008269709,0.00003401044,0.0002668168,0.00003150288,0.0007852123,0.9915749,0.00007191089,0.003143489,0.000007714879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958602,0.001418824,0.0009059128,0.0002647696,0.00004830115,0.00001927024,0.0004326002,0.0001436672,0.0009064594],"genre_scores_gemma":[0.9945721,0.001175324,0.0008653166,0.0001469571,0.0000155878,0.00004104057,0.0008143846,0.00003982435,0.002329505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009926627,"threshold_uncertainty_score":0.003320754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04273684218544106,"score_gpt":0.3389543616843697,"score_spread":0.2962175194989286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}