{"id":"W2317119148","doi":"10.1016/j.ijbiomac.2016.03.060","title":"An overview on the delivery of antitumor drug doxorubicin by carrier proteins","year":2016,"lang":"en","type":"review","venue":"International Journal of Biological Macromolecules","topic":"Protein Interaction Studies and Fluorescence Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Doxorubicin; Bovine serum albumin; Chemistry; Drug delivery; Human serum albumin; In vivo; Drug; In vitro; Serum albumin; Drug carrier; Plasma protein binding; Pharmacology; Albumin; Blood proteins; Biochemistry; Medicine; Biology; Chemotherapy; Biotechnology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004411576,0.0003024452,0.0007926642,0.0001095662,0.00005906307,0.00004195329,0.001182523,0.0001902397,0.0001501368],"category_scores_gemma":[0.0002675341,0.0001384781,0.000893474,0.00008770567,0.0002225298,0.000009453186,0.0001888915,0.0002616406,0.00001316705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004399116,"about_ca_system_score_gemma":0.000106095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001756922,"about_ca_topic_score_gemma":0.000002846505,"domain_scores_codex":[0.9978677,0.0003921647,0.000874589,0.00030024,0.0003881855,0.0001771372],"domain_scores_gemma":[0.99773,0.0001157349,0.001224839,0.0002950879,0.0005566998,0.00007762831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004789515,0.0006677341,0.0001061781,0.0003738826,0.00457891,0.0001501771,0.00002676607,0.00000190294,0.1344916,0.001165476,0.01361755,0.8443409],"study_design_scores_gemma":[0.0002010212,0.0006863187,0.00001210863,0.003520695,0.0001391671,0.0001233681,0.00004368882,7.291081e-7,0.02046441,0.0001084465,0.9744666,0.0002334202],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006697002,0.9914762,0.0002589646,0.0003590545,0.0003315702,0.0002414014,0.0005199102,0.00000334024,0.0001124904],"genre_scores_gemma":[0.03163332,0.9673089,0.00008807985,0.0002959808,0.0004743399,0.00002475789,0.00007641733,0.00001750268,0.00008066494],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9608491,"threshold_uncertainty_score":0.5646974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04578083477999886,"score_gpt":0.3580294025506997,"score_spread":0.3122485677707009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}