{"id":"W2317176158","doi":"10.1074/jbc.m115.668533","title":"Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Research Council; Institute of Genetics; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Agence Nationale pour le Développement de la Recherche en Santé; Centre National de la Recherche Scientifique; European Commission; Association pour la Recherche sur le Cancer","keywords":"Histone acetyltransferase; Coactivator; Histone; Acetylation; Biology; Chromatin; P300-CBP Transcription Factors; Acetyltransferase; Histone Acetyltransferases; Protein subunit; PCAF; Molecular biology; Biochemistry; Transcription factor; DNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006840268,0.0002711841,0.000570014,0.00002111007,0.0000674051,0.00001956897,0.0006124969,0.0002744515,0.00005872336],"category_scores_gemma":[0.0005660411,0.0001662485,0.000263725,0.0001339982,0.0003640539,0.00001241456,0.0001420896,0.0003119263,6.712821e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004417971,"about_ca_system_score_gemma":0.0003890008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001958011,"about_ca_topic_score_gemma":0.0000115657,"domain_scores_codex":[0.9983478,0.0001305156,0.000691489,0.000259495,0.0002755553,0.0002951004],"domain_scores_gemma":[0.9980741,0.0001448162,0.0007350724,0.0003908396,0.0004306155,0.0002245177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001794627,0.0002680726,0.002754285,0.00006687323,0.0001560516,0.00001454531,0.00007046763,0.0001798898,0.9937092,0.00001162264,0.0001920691,0.0007822893],"study_design_scores_gemma":[0.001290527,0.001051078,0.001317304,0.00006054897,0.00004598974,0.0001871387,0.0005656664,0.00009166279,0.9941552,0.00007549619,0.0009470633,0.0002122803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973183,0.0005966083,0.001226329,0.0001684238,0.00009443783,0.0001170522,0.000142929,0.000005195359,0.0003307628],"genre_scores_gemma":[0.9983049,0.0003622921,0.0008424409,0.00008009323,0.0002692214,0.000003973245,0.00003775524,0.00001849768,0.00008083327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001436981,"threshold_uncertainty_score":0.6779418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03999578931342915,"score_gpt":0.282945993786992,"score_spread":0.2429502044735628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}