{"id":"W2317207768","doi":"10.1107/s0108767309096998","title":"Conformational change of adenosine deaminase during ligand-exchange in crystal state","year":2009,"lang":"en","type":"article","venue":"Acta Crystallographica Section A Foundations of Crystallography","topic":"Crystallization and Solubility Studies","field":"Materials Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology","funders":"","keywords":"Adenosine deaminase; Ligand (biochemistry); Conformational change; Adenosine; Chemistry; Biophysics; Biochemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007258753,0.0004049258,0.0006946552,0.002410368,0.0003252184,0.00009194001,0.0004178013,0.0001966482,0.0005055096],"category_scores_gemma":[0.0001686333,0.0004272669,0.0003832359,0.002949506,0.000656012,0.001345665,0.0001097083,0.0002498494,9.102832e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007505126,"about_ca_system_score_gemma":0.00008549151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001988658,"about_ca_topic_score_gemma":0.0007730368,"domain_scores_codex":[0.9964938,0.0001851709,0.001473606,0.0005448217,0.0007460222,0.0005565778],"domain_scores_gemma":[0.9976339,0.0001604058,0.0008192548,0.0005504343,0.0006758526,0.0001601812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003575465,0.001012468,0.01612238,0.0003309414,0.00006583595,0.000005442041,0.003764702,0.0001614017,0.9769595,0.0007858627,0.0001275035,0.0003063781],"study_design_scores_gemma":[0.004773042,0.001031313,0.9593868,0.000393809,0.0001253377,0.00005183682,0.002522764,0.0003249472,0.008543887,0.005204808,0.01650677,0.001134639],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949949,0.0003120436,0.001377381,0.0006834305,0.0002831342,0.0009350099,0.0002090701,0.0001728237,0.001032179],"genre_scores_gemma":[0.9980712,0.000523561,0.0008414076,0.0001269964,0.00008103177,0.0001135851,0.0001621538,0.00002654978,0.00005350054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9684156,"threshold_uncertainty_score":0.9998179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0196819225149577,"score_gpt":0.262354616163445,"score_spread":0.2426726936484873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}