{"id":"W2317369246","doi":"10.1055/s-2009-1216410","title":"Relative and Absolute Structures of Diospongin A, B and C","year":2009,"lang":"en","type":"article","venue":"Planta Medica","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Drug Abuse; Agricultural Research Service; University of British Columbia; University of Illinois at Urbana-Champaign; Chinese Academy of Sciences; Kurukshetra University; University of Illinois at Chicago; National Oceanic and Atmospheric Administration; U.S. Food and Drug Administration; National Science Foundation of Sri Lanka; University of Colombo; U.S. Department of Agriculture; Western Carolina University; International Science Council; National Center for Complementary and Alternative Medicine; China Academy of Traditional Chinese Medicine; National Institutes of Health; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Hong Kong Polytechnic University; National Science Foundation; Deutsche Krebshilfe; National Natural Science Foundation of China; Tata Trusts; University Grants Commission; Wake Forest University","keywords":"Chemistry; Absolute configuration; Stereochemistry; Diarylheptanoids; Osteoclast; NMR spectra database; Spectral line; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007175621,0.00006230781,0.0000935471,0.00001635597,0.00002728581,0.000004022276,0.00004044751,0.00007038165,0.000008917576],"category_scores_gemma":[0.00007889305,0.00004689843,0.00001416509,0.00001716102,0.00008577583,0.000002800423,0.00002346215,0.00005138569,1.65329e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001343526,"about_ca_system_score_gemma":0.000009859947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001262348,"about_ca_topic_score_gemma":0.000004024454,"domain_scores_codex":[0.999621,0.00001695759,0.00007420051,0.0001410986,0.00006452276,0.00008216068],"domain_scores_gemma":[0.999805,0.00001866864,0.00003610041,0.00008685557,0.000009726905,0.00004365426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002728429,0.00002471086,0.001233447,0.00003742127,0.0001086508,0.000009063785,0.0002857368,3.753242e-7,0.8990666,0.001955071,0.004446748,0.0925593],"study_design_scores_gemma":[0.0009526515,0.0009046418,0.2260592,0.00006576881,0.00009095898,0.0002435046,0.0002805375,0.00005729906,0.7260631,0.005657889,0.0392082,0.0004162563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994292,0.003953965,0.00003302654,0.0007785067,0.00003930119,0.000046375,0.00002753215,0.000003216489,0.0008260399],"genre_scores_gemma":[0.9980807,0.00111351,0.000381708,0.0001262231,0.00007620431,4.327123e-7,0.00001790969,0.000002734854,0.0002006191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2248257,"threshold_uncertainty_score":0.1912463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00499200683497432,"score_gpt":0.2167879361012404,"score_spread":0.2117959292662661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}