{"id":"W2317490780","doi":"10.1097/cji.0b013e3181eccc87","title":"Preclinical Qualification of a New Multi-antigen Candidate Vaccine for Metastatic Melanoma","year":2010,"lang":"en","type":"article","venue":"Journal of Immunotherapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Learning Partnership; Sanofi (Canada)","funders":"","keywords":"Antigen; Immunogenicity; Immunology; Immune system; Cytotoxic T cell; Antigen presentation; Biology; Melanoma; Ex vivo; Medicine; T cell; Cancer research; Virology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004186901,0.0004401059,0.0002824689,0.000234665,0.0001082301,0.0003299016,0.0002600114,0.0005788664,0.001467496],"category_scores_gemma":[0.0002142862,0.0001332885,0.0002692652,0.00007495115,0.0001477618,0.0002730986,0.0001759659,0.0008525151,0.0003695186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002063648,"about_ca_system_score_gemma":0.000257484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002440745,"about_ca_topic_score_gemma":0.0003292742,"domain_scores_codex":[0.9998292,0.00004885648,0.000009892154,0.00002427681,0.0000508025,0.0000369692],"domain_scores_gemma":[0.9998755,0.00002271432,0.00002294547,0.00001722529,0.00002544419,0.00003612616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002084459,0.0004330487,0.000234494,0.00008010245,0.00001267105,0.00003989453,0.00001689391,0.0006047612,0.9934481,0.0001437715,0.00009126376,0.004686651],"study_design_scores_gemma":[0.0001688296,0.02540229,0.001666249,0.00003138125,0.00006229448,0.0003337132,0.00002441393,0.002390775,0.9626954,0.0001456867,0.007072211,0.000006734036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830521,0.002328964,0.01093175,0.0002023121,0.0001429661,0.0007756046,0.0003894562,0.0001098914,0.002066935],"genre_scores_gemma":[0.9849293,0.001909807,0.009051583,0.00009744072,0.0000539555,0.0003514166,0.0008073965,0.00002701958,0.002771953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001467496,"threshold_uncertainty_score":0.004909277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04058313421163846,"score_gpt":0.3532582963415023,"score_spread":0.3126751621298638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}