{"id":"W2317490780","doi":"10.1097/cji.0b013e3181eccc87","title":"Preclinical Qualification of a New Multi-antigen Candidate Vaccine for Metastatic Melanoma","year":2010,"lang":"en","type":"article","venue":"Journal of Immunotherapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Learning Partnership; Sanofi (Canada)","funders":"","keywords":"Antigen; Immunogenicity; Immunology; Immune system; Cytotoxic T cell; Antigen presentation; Biology; Melanoma; Ex vivo; Medicine; T cell; Cancer research; Virology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001555304,0.000217503,0.0007051848,0.0002553904,0.0001147659,0.00001964026,0.0005201153,0.0002159799,0.0007600997],"category_scores_gemma":[0.0004081826,0.0001640422,0.000463686,0.0001419638,0.0001082128,0.0001983335,0.0000169559,0.0004978508,0.00002517927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001953157,"about_ca_system_score_gemma":0.0004137634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001371362,"about_ca_topic_score_gemma":0.00003290243,"domain_scores_codex":[0.997795,0.0002908438,0.001398996,0.0001591283,0.00007211485,0.0002838714],"domain_scores_gemma":[0.9970943,0.0006861491,0.001397697,0.0004260679,0.0003655425,0.00003026147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007667241,0.0004487291,0.001592827,0.00001493428,0.001180337,0.000001295007,0.00132729,0.00000285365,0.9264497,0.0001609081,0.001649985,0.05950389],"study_design_scores_gemma":[0.01693888,0.002200954,0.03131077,0.00009352285,0.0001124637,0.0003415909,0.000269959,0.00001050023,0.7538843,0.0003073332,0.1942798,0.0002498937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9564773,0.0246681,0.0157559,0.0006775847,0.001922142,0.0004362717,0.00003353162,0.00001562684,0.00001356701],"genre_scores_gemma":[0.9783106,0.004100931,0.01409368,0.0002536033,0.0001239014,0.00001465892,0.00003145538,0.00005783476,0.003013354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1926299,"threshold_uncertainty_score":0.832256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04058313421163846,"score_gpt":0.3532582963415023,"score_spread":0.3126751621298638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}