{"id":"W2317767830","doi":"10.1158/0008-5472.sabcs-77","title":"BCIRG 005 main efficacy analysis: a phase III randomized trial comparing docetaxel in combination with doxorubicin and cyclophosphamide (TAC) versus doxorubicin and cyclophosphamide followed by docetaxel (AC→T) in women with Her-2/neu negative axillary lymph node positive early breast cancer.","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital du Saint-Sacrement; William Osler Health System","funders":"","keywords":"Medicine; Docetaxel; Internal medicine; Anthracycline; Febrile neutropenia; Breast cancer; Neutropenia; Cyclophosphamide; Regimen; Mucositis; Clinical endpoint; Metastatic breast cancer; Chemotherapy; Gastroenterology; Doxorubicin; Cancer; Oncology; Surgery; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001665287,0.001506994,0.001820459,0.0005436135,0.0003490602,0.0009976665,0.001165115,0.001504902,0.01385286],"category_scores_gemma":[0.001981048,0.000456137,0.001160297,0.0005544744,0.0007519421,0.0006732136,0.0003614058,0.003168846,0.001577181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001162686,"about_ca_system_score_gemma":0.001511713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002057484,"about_ca_topic_score_gemma":0.005581817,"domain_scores_codex":[0.9990761,0.0006523174,0.00002986058,0.00008466046,0.00006323981,0.00009373732],"domain_scores_gemma":[0.9993,0.000181442,0.0001650492,0.00002967585,0.00003368219,0.0002900297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9631972,0.004326476,0.0005108239,0.000934162,0.0008085759,0.00004154239,0.00002410683,0.0004395107,0.001807575,0.0002146746,0.003042401,0.02465304],"study_design_scores_gemma":[0.9693115,0.02771583,0.001054834,0.00005120597,0.0003028034,0.00002358081,0.000007356708,0.0002680999,0.0001416731,0.0001136209,0.001002711,0.000006777692],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9205118,0.02423196,0.001379733,0.004123359,0.001470964,0.01344521,0.008060054,0.0005154542,0.02626141],"genre_scores_gemma":[0.9579361,0.005915748,0.002842614,0.00427326,0.0007204444,0.00981098,0.005031117,0.00006500209,0.01340476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01385286,"threshold_uncertainty_score":0.04634243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02207255447226454,"score_gpt":0.3666933726283754,"score_spread":0.3446208181561108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}