{"id":"W2317790835","doi":"10.1038/sj.onc.1205787","title":"The ubiquitous and tissue specific promoters of the human SRC gene are repressed by inhibitors of histone deacetylases","year":2002,"lang":"en","type":"article","venue":"Oncogene","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Trichostatin A; Sodium butyrate; Biology; Histone deacetylase; Promoter; HDAC4; Cancer research; HDAC11; HDAC10; Histone deacetylase 2; Histone deacetylase inhibitor; Proto-oncogene tyrosine-protein kinase Src; Histone deacetylase 5; Molecular biology; Histone; Cell biology; Gene expression; Signal transduction; Biochemistry; Cell culture; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001643701,0.0004062794,0.0002748019,0.0003950372,0.0002010605,0.0004438076,0.000201212,0.0001422414,0.001718113],"category_scores_gemma":[0.0003155031,0.0002433718,0.0003017143,0.0002730591,0.0003163805,0.0001645677,0.0003293115,0.0004459477,0.0005887412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004474442,"about_ca_system_score_gemma":0.0003428455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009594059,"about_ca_topic_score_gemma":0.002704015,"domain_scores_codex":[0.9997374,0.00002136503,0.00001556067,0.00005040936,0.00007209117,0.0001030552],"domain_scores_gemma":[0.9996918,0.00006856622,0.00008532422,0.00003852155,0.00003991137,0.00007585261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001754462,0.00001807112,0.0004246717,0.00001978621,0.000004419206,0.00005274844,0.00001736353,0.00003390904,0.9969523,0.0003626634,0.00005941825,0.001879335],"study_design_scores_gemma":[0.00003488086,0.0001788852,0.01494045,0.000007058594,0.0000261531,0.0007565534,0.00004907998,0.0006378372,0.9793019,0.0002112421,0.003850029,0.000005855649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796572,0.007094122,0.006427806,0.0001560936,0.00007458348,0.00003064226,0.0007146792,0.0001985813,0.005646224],"genre_scores_gemma":[0.9915096,0.001619098,0.001341051,0.00003807191,0.0000303474,0.00002356331,0.001619781,0.00004953225,0.003768971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001718113,"threshold_uncertainty_score":0.005747616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01522092222160471,"score_gpt":0.2861961904230984,"score_spread":0.2709752682014937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}