{"id":"W2317940640","doi":"10.1371/journal.pone.0123689","title":"5Z-7-Oxozeanol Inhibits the Effects of TGFβ1 on Human Gingival Fibroblasts","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"CTGF; Transforming growth factor; CYR61; Extracellular matrix; Fibrosis; Connective tissue; Cancer research; Transforming growth factor beta; Gene expression profiling; Biology; Cell biology; Myofibroblast; Growth factor; Fibroblast; Gene expression; Pathology; Medicine; Cell culture; Gene; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008813517,0.000393349,0.0002741929,0.00021314,0.0001278295,0.0001692506,0.0001070255,0.0001569229,0.001775893],"category_scores_gemma":[0.00006146669,0.00009026016,0.0003031719,0.0001200659,0.0001203336,0.00009938446,0.0001152851,0.0004102591,0.0003356886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001573984,"about_ca_system_score_gemma":0.0002350356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001001264,"about_ca_topic_score_gemma":0.001502941,"domain_scores_codex":[0.9999363,0.00001073824,0.000006961277,0.000009837929,0.00001185437,0.00002431961],"domain_scores_gemma":[0.99997,0.000006851347,0.000006791783,0.00000335769,0.000004038276,0.000009027183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005992774,0.0001544517,0.0001396861,0.000134144,0.00000853028,0.00004743605,0.00002070356,0.00006430939,0.9943105,0.00003389953,0.00006564173,0.004421435],"study_design_scores_gemma":[0.0001216047,0.003001493,0.007710054,0.0000189224,0.00003945926,0.0001937452,0.00009876033,0.0005533162,0.9849416,0.00004719675,0.003266588,0.000007101181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905901,0.005965402,0.0009849267,0.0001457092,0.00007096786,0.00004486434,0.0004755053,0.00007832266,0.001644234],"genre_scores_gemma":[0.9924084,0.003684567,0.001024299,0.00008647233,0.00001717001,0.00003488188,0.0006112665,0.000007826192,0.00212512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001775893,"threshold_uncertainty_score":0.005940974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07612049993860878,"score_gpt":0.2985889240344398,"score_spread":0.222468424095831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}