{"id":"W2318023690","doi":"10.1021/jo0158229","title":"Synthesis of Boroxifen, A <i>N</i><i>ido-</i>Carborane Analogue of Tamoxifen","year":2001,"lang":"he","type":"article","venue":"The Journal of Organic Chemistry","topic":"Boron Compounds in Chemistry","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Carborane; Tamoxifen; Chemistry; Prodrug; Boron; Acetonitrile; Antiestrogen; Decaborane; Stereochemistry; Nuclear magnetic resonance spectroscopy; Combinatorial chemistry; Organic chemistry; Breast cancer; Cancer; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000622779,0.0001929985,0.0002375845,0.0001296965,0.000183968,0.0001624939,0.0002437984,0.0001673975,0.002095114],"category_scores_gemma":[0.00009414589,0.000116504,0.0001530729,0.0001499841,0.00008810988,0.0001307568,0.0001702639,0.0002402483,0.0007025573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001845435,"about_ca_system_score_gemma":0.0003264165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006697553,"about_ca_topic_score_gemma":0.001504656,"domain_scores_codex":[0.9999425,0.000007322152,0.000005644399,0.00001184111,0.00001365956,0.00001900724],"domain_scores_gemma":[0.9999679,0.000002351362,0.000004787601,0.000004810412,0.000007931135,0.00001211423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001201156,0.00003733607,0.00008161918,0.0001479574,0.000007883385,0.000178487,0.00004713649,0.0003014844,0.990388,0.00130859,0.0001836621,0.007197762],"study_design_scores_gemma":[0.00007734382,0.0005883781,0.0005845496,0.00001293061,0.00001955243,0.0004589872,0.0000341713,0.0005299307,0.9664292,0.0001631699,0.03108857,0.00001335721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9102293,0.005520972,0.03390435,0.000355164,0.0002857273,0.0005918465,0.001812433,0.0003409047,0.0469593],"genre_scores_gemma":[0.9640568,0.003646148,0.0171311,0.00009627621,0.00002643294,0.0001191906,0.001106927,0.00005095209,0.01376617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002095114,"threshold_uncertainty_score":0.007008791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01216966486950367,"score_gpt":0.2462112571292117,"score_spread":0.2340415922597081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}