{"id":"W2318097039","doi":"10.1021/om300354x","title":"1,1′-Disubstituted Ferrocenyl Carbohydrate Chloroquine Conjugates as Potential Antimalarials","year":2012,"lang":"en","type":"article","venue":"Organometallics","topic":"Ferrocene Chemistry and Applications","field":"Chemistry","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"TRIUMF; Advanced Applied Physics Solutions; University of British Columbia","funders":"","keywords":"Chemistry; Ferrocene; Moiety; Stereochemistry; Plasmodium falciparum; Chloroquine; Reductive amination; Conjugate; Combinatorial chemistry; Structural isomer; Adamantane; Organic chemistry; Malaria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005442155,0.0002730359,0.0001672167,0.0001164112,0.00005910807,0.0001133935,0.000183979,0.0001465233,0.0004696413],"category_scores_gemma":[0.00005743813,0.00006241256,0.00008425885,0.00009542884,0.0001053702,0.0001143491,0.0001096668,0.0002145076,0.0001743437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002135613,"about_ca_system_score_gemma":0.0001247456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004357996,"about_ca_topic_score_gemma":0.0009377153,"domain_scores_codex":[0.999961,0.000008246893,0.000002034831,0.000006875931,0.000009081891,0.00001278203],"domain_scores_gemma":[0.9999765,0.000002537168,0.000006811118,0.000002765292,0.000005390022,0.000005996614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001338814,0.00002275785,0.0001706507,0.00008616683,0.00000671209,0.0001007553,0.00001881968,0.0003239095,0.9923051,0.000336992,0.00007079534,0.006423449],"study_design_scores_gemma":[0.00003471363,0.0007859142,0.001400218,0.000009413694,0.00002432727,0.0003724831,0.00001597269,0.0005966704,0.9875225,0.00004942056,0.009179912,0.000008283473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872075,0.004113323,0.004549676,0.00009489842,0.00003777139,0.00004137739,0.0001575583,0.00007385546,0.003724013],"genre_scores_gemma":[0.9935611,0.001816983,0.002824228,0.00004688042,0.00000972956,0.00001755629,0.0001346739,0.000007996291,0.001580829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004696413,"threshold_uncertainty_score":0.001571178,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194169449514436,"score_gpt":0.2407638947807559,"score_spread":0.2288222002856116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}