{"id":"W2318236826","doi":"10.1021/la400890f","title":"Multifunctional Dendritic Sialopolymersomes as Potential Antiviral Agents: Their Lectin Binding and Drug Release Properties","year":2013,"lang":"en","type":"article","venue":"Langmuir","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Lectin; Drug; Biophysics; Combinatorial chemistry; Nanotechnology; Stereochemistry; Biochemistry; Materials science; Pharmacology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001327759,0.0002323461,0.0001741381,0.0001312489,0.00006818974,0.000256978,0.0001425051,0.0003247862,0.0005252603],"category_scores_gemma":[0.0001168739,0.0000830885,0.0001749005,0.00009301936,0.0001130998,0.0002492518,0.0001294615,0.0002448532,0.0002505142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002628175,"about_ca_system_score_gemma":0.000121306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002948972,"about_ca_topic_score_gemma":0.0003955552,"domain_scores_codex":[0.9999473,0.00001093688,0.00000355524,0.00001098427,0.00001518126,0.00001204916],"domain_scores_gemma":[0.9999501,0.00001007656,0.00001075188,0.000003908601,0.00001072601,0.00001448248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006759925,0.0000130444,0.00005011577,0.00003398838,0.000002688206,0.00002575373,0.000004810969,0.0001301392,0.9974624,0.00007409619,0.00001250002,0.002122747],"study_design_scores_gemma":[0.00001364818,0.0001638177,0.0006470488,0.000003470079,0.00001132024,0.00008302821,0.00000518489,0.001167239,0.9963843,0.00002580356,0.001491343,0.000003849425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834253,0.00554946,0.00776432,0.0001375717,0.00003137741,0.0000778504,0.0002903726,0.00006497601,0.002658707],"genre_scores_gemma":[0.9900733,0.001994142,0.00571738,0.00005155325,0.00001230981,0.00003980218,0.0001650537,0.00001264534,0.001933872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005252603,"threshold_uncertainty_score":0.001906812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01032636443479225,"score_gpt":0.2128795781526405,"score_spread":0.2025532137178483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}