{"id":"W2318345956","doi":"10.1139/bcb-2013-0103","title":"A new mechanism in the binding between Homer3 EVH1 domain and inositol 1,4,5 trisphosphate receptor suppressor domain","year":2014,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Binding domain; Suppressor; Binding site; Mutant; Inositol; HAMP domain; Biophysics; C2 domain; Biology; Calmodulin; Cell biology; Chemistry; Receptor; Biochemistry; Gene; Enzyme; Membrane","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002108276,0.0004756402,0.0004261965,0.0001910609,0.0003096776,0.0003613428,0.000726849,0.0008560862,0.0018414],"category_scores_gemma":[0.0001696977,0.0002369604,0.0005286411,0.0001033275,0.0005307387,0.0008591572,0.0003957204,0.0007055199,0.0005920149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003257263,"about_ca_system_score_gemma":0.0002716895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003573908,"about_ca_topic_score_gemma":0.0004123979,"domain_scores_codex":[0.9997838,0.00002147822,0.00001181332,0.0000788918,0.00005749526,0.00004655718],"domain_scores_gemma":[0.999891,0.00001805441,0.00003167364,0.00001910139,0.00001223356,0.00002783177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001150129,0.00005641739,0.0006333841,0.00008505061,0.00002281167,0.001089961,0.00005773679,0.0003022146,0.9918555,0.003017472,0.0001412609,0.002623142],"study_design_scores_gemma":[0.0001181046,0.000504992,0.01138461,0.00001723845,0.00006228273,0.005045657,0.0001326109,0.01561796,0.9555364,0.002581703,0.008947775,0.00005065309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9428237,0.002452271,0.04931127,0.0005925956,0.0002300731,0.00008985869,0.0001601097,0.0006392133,0.0037009],"genre_scores_gemma":[0.9847312,0.0004414921,0.01116555,0.0002126924,0.00003257463,0.00004122778,0.0001535671,0.00001856614,0.003203202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0018414,"threshold_uncertainty_score":0.00616008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007182990561486217,"score_gpt":0.2199355244493099,"score_spread":0.2127525338878236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}