{"id":"W2318577602","doi":"10.1158/1538-7445.am2011-4249","title":"Abstract 4249: NGR-TNF, a novel direct-acting vascular targeting agent, does not induce “cytokine-rebound” recruitment of pro-angiogenic bone-marrow derived cells","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Bone marrow; Cancer research; Angiogenesis; Lewis lung carcinoma; Homing (biology); Tumor necrosis factor alpha; Cytokine; Immunology; Medicine; Biology; Internal medicine; Cancer; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009551214,0.0002561402,0.000177785,0.000108965,0.00008923898,0.0001317924,0.0001597802,0.000255849,0.00443816],"category_scores_gemma":[0.00008001297,0.00005634749,0.0001152277,0.00007259538,0.0001587786,0.0001388097,0.00007882307,0.0004457624,0.00102513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001790401,"about_ca_system_score_gemma":0.0001532945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000289826,"about_ca_topic_score_gemma":0.0003646683,"domain_scores_codex":[0.999892,0.00002076949,0.00000916546,0.00002086263,0.00003172422,0.00002551029],"domain_scores_gemma":[0.9999324,0.00001512494,0.00001862884,0.000008283039,0.000006730019,0.00001893565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003683327,0.0001228397,0.00008324108,0.00004224475,0.000002891366,0.00005973782,0.000006148425,0.00005101058,0.9961629,0.0001082558,0.0002140645,0.002778353],"study_design_scores_gemma":[0.00009153676,0.001382019,0.00104891,0.000007053315,0.000009703212,0.0003647091,0.00000548897,0.000429898,0.9912912,0.00002186924,0.005345495,0.000002082275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834718,0.003175965,0.003590663,0.0002608015,0.0001358329,0.00008474934,0.0007787847,0.0001834535,0.008317869],"genre_scores_gemma":[0.9860276,0.0008873934,0.002713633,0.0001080881,0.00005301676,0.00007215389,0.001534609,0.00002924559,0.00857425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00443816,"threshold_uncertainty_score":0.01484716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2232917587740333,"score_gpt":0.3981785280428668,"score_spread":0.1748867692688335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}