{"id":"W2318668917","doi":"10.1074/jbc.m114.624247","title":"The Interaction of Protein-tyrosine Phosphatase α (PTPα) and RACK1 Protein Enables Insulin-like Growth Factor 1 (IGF-1)-stimulated Abl-dependent and -independent Tyrosine Phosphorylation of PTPα","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Phosphorylation; Protein tyrosine phosphatase; Tyrosine phosphorylation; Cell biology; Proto-oncogene tyrosine-protein kinase Src; Scaffold protein; Biology; Receptor tyrosine kinase; Signal transduction; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001063879,0.0003180093,0.0001374741,0.0001112584,0.00017884,0.0002164117,0.0001647425,0.0001997488,0.001469786],"category_scores_gemma":[0.00009503915,0.0001533456,0.000277276,0.00009748673,0.0001243219,0.0001397155,0.0002459536,0.0004526758,0.0004571804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003819764,"about_ca_system_score_gemma":0.0001411109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00056979,"about_ca_topic_score_gemma":0.0008416068,"domain_scores_codex":[0.9998323,0.00001828123,0.00001235996,0.00004479447,0.00003896706,0.00005324978],"domain_scores_gemma":[0.9999388,0.000008182283,0.00002306446,0.000006689224,0.000003929996,0.00001934163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006357855,0.00001928361,0.0002888488,0.00001968272,0.000005030592,0.00005796594,0.000009801774,0.00005189447,0.9986776,0.0001511227,0.00003224279,0.0006230745],"study_design_scores_gemma":[0.00002546923,0.0001829153,0.0106631,0.000007334949,0.00002007224,0.0009487392,0.00002710384,0.002182153,0.9809442,0.00007293867,0.004921288,0.000004538535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960948,0.0007458664,0.001735731,0.00006670742,0.00002126138,0.00001207669,0.0001307961,0.00003000752,0.001162882],"genre_scores_gemma":[0.9965867,0.000366712,0.001165007,0.00001625391,0.00000673913,0.00001425209,0.0003601231,0.000005362485,0.001478708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001469786,"threshold_uncertainty_score":0.004916966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02148496537393954,"score_gpt":0.2555723252039167,"score_spread":0.2340873598299771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}