{"id":"W2318680867","doi":"10.1021/bc2001159","title":"Well-Controlled Cationic Water-Soluble Phospholipid Polymer−DNA Nanocomplexes for Gene Delivery","year":2011,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene delivery; Copolymer; Cationic polymerization; Chemistry; Biocompatibility; Polymer; Transfection; Raft; Phosphorylcholine; Chain transfer; Polymerization; Biophysics; Polymer chemistry; Nanotechnology; Radical polymerization; Gene; Biochemistry; Organic chemistry; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003989397,0.000427669,0.00024676,0.0003392798,0.0001597339,0.0003480149,0.0002234511,0.0003646094,0.0006494002],"category_scores_gemma":[0.0004863402,0.0002409094,0.0001418044,0.0002309515,0.000233109,0.0004571296,0.0002370901,0.0004917425,0.0004278673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000595289,"about_ca_system_score_gemma":0.0003309043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003241434,"about_ca_topic_score_gemma":0.0009320235,"domain_scores_codex":[0.9997546,0.0000445894,0.00002787482,0.00006394988,0.00007966459,0.00002936048],"domain_scores_gemma":[0.9998068,0.00004777639,0.00006558417,0.00001430191,0.00002945903,0.00003611362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001757024,0.000009542568,0.00001919988,0.0000304588,0.000001763222,0.0000157322,0.00001000125,0.0001346788,0.9979041,0.0001160715,0.00002008463,0.001720874],"study_design_scores_gemma":[0.00001301476,0.00007125962,0.0001265404,0.000002794144,0.000004595654,0.00004492184,0.000003268543,0.001018649,0.9973145,0.00003641627,0.001359295,0.000004703363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9269441,0.008752145,0.05993157,0.0002792364,0.0001049216,0.0003444481,0.0003600117,0.0004842233,0.002799331],"genre_scores_gemma":[0.9567062,0.002777191,0.03678828,0.00009600502,0.00002111182,0.0001744052,0.0002198007,0.00007175696,0.003145258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006494002,"threshold_uncertainty_score":0.004319131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0190877278674882,"score_gpt":0.2227572020039534,"score_spread":0.2036694741364652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}