{"id":"W2318680867","doi":"10.1021/bc2001159","title":"Well-Controlled Cationic Water-Soluble Phospholipid Polymer−DNA Nanocomplexes for Gene Delivery","year":2011,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene delivery; Copolymer; Cationic polymerization; Chemistry; Biocompatibility; Polymer; Transfection; Raft; Phosphorylcholine; Chain transfer; Polymerization; Biophysics; Polymer chemistry; Nanotechnology; Radical polymerization; Gene; Biochemistry; Organic chemistry; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000165967,0.0003453759,0.0003502897,0.00002844698,0.0001789303,0.00004873006,0.00048549,0.0002967426,0.0005973444],"category_scores_gemma":[0.00002323956,0.0002910697,0.0003413945,0.00004715009,0.0001296663,0.00001154149,0.0001505488,0.0000835783,0.0001235327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002848683,"about_ca_system_score_gemma":0.0001131095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008922596,"about_ca_topic_score_gemma":0.00001422007,"domain_scores_codex":[0.9982102,0.00002187217,0.0004389359,0.000643693,0.0001193012,0.0005660173],"domain_scores_gemma":[0.9988495,0.00001080139,0.0001325739,0.0006425555,0.0002037416,0.0001608135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001064448,0.000122721,0.0001371584,0.00005762664,0.0001953551,0.000002806726,0.00008323997,0.000001854227,0.994512,0.00001383095,0.003560572,0.0002483933],"study_design_scores_gemma":[0.003097596,0.000185946,0.00004731723,0.00001603316,0.00007178594,0.00002494127,0.00008899724,0.00003226344,0.9778731,0.0001033386,0.0180365,0.0004221974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912171,0.001613288,0.0001915001,0.00006931746,0.0003445014,0.0005303503,0.00008645621,0.00004369612,0.005903799],"genre_scores_gemma":[0.9836004,0.0003206314,0.0004637659,0.0003584965,0.0005448271,0.0003796658,0.0007767075,0.00005305086,0.01350241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01663891,"threshold_uncertainty_score":0.9999542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0190877278674882,"score_gpt":0.2227572020039534,"score_spread":0.2036694741364652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}