{"id":"W2318685045","doi":"10.1097/00002030-200108170-00019","title":"Non-nucleoside reverse transcriptase inhibitor failure impairs HIV-RNA responses to efavirenz-containing salvage antiretroviral therapy","year":2001,"lang":"en","type":"article","venue":"AIDS","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Toronto General Hospital; University of British Columbia; Memorial University of Newfoundland; University Health Network","funders":"","keywords":"Efavirenz; Reverse transcriptase; Nucleoside Reverse Transcriptase Inhibitor; Reverse-transcriptase inhibitor; Virology; Salvage therapy; Viral load; Medicine; Retrospective cohort study; Antiretroviral therapy; Human immunodeficiency virus (HIV); Internal medicine; Oncology; Biology; RNA; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003593534,0.0003960711,0.0005392825,0.0004858399,0.0001926638,0.00005363318,0.0001491634,0.0001440543,0.0004045931],"category_scores_gemma":[0.00007625025,0.0003239486,0.0002492887,0.0007204468,0.00006635686,0.0002323247,0.00003617307,0.000260074,0.0005676743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001840159,"about_ca_system_score_gemma":0.0001929735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008412574,"about_ca_topic_score_gemma":0.00001389572,"domain_scores_codex":[0.9979364,0.00008143039,0.0004365521,0.0005136177,0.0004260316,0.000605975],"domain_scores_gemma":[0.9988962,0.00007838562,0.00006995934,0.0004633797,0.00007776172,0.0004142464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006649615,0.0005905214,0.7463025,0.00003965792,0.0004584492,0.003025595,0.007329681,0.000001703879,0.1080234,0.00008774736,0.08075329,0.04673786],"study_design_scores_gemma":[0.02350745,0.008846049,0.1687838,0.0009282517,0.0004964987,0.0003615301,0.005572937,0.00005891078,0.1011235,0.00005617884,0.6887613,0.001503663],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989001,0.0002597487,0.0001423535,0.006875243,0.0002293402,0.0007771298,0.00003161577,0.0002046057,0.002478987],"genre_scores_gemma":[0.9601221,0.0001317388,0.006086942,0.002338325,0.000304059,0.00007115218,0.00008207088,0.00007275383,0.03079082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.608008,"threshold_uncertainty_score":0.9999213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0161043363835187,"score_gpt":0.2681944168319753,"score_spread":0.2520900804484566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}