{"id":"W2318763430","doi":"10.1097/pai.0000000000000089","title":"Protein Expression for Novel Prognostic Markers (Cyclins D1, D2, D3, B1, B2, ITGβ7, FGFR3, PAX5) Correlate With Previously Reported Gene Expression Profile Patterns in Plasma Cell Myeloma","year":2014,"lang":"en","type":"article","venue":"Applied immunohistochemistry & molecular morphology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; Foothills Medical Centre; University of Calgary","funders":"","keywords":"Cyclin D1; Cyclin; Multiple myeloma; Cyclin D3; Immunohistochemistry; Plasma Cell Myeloma; Cyclin D2; Cancer research; Gene expression; Pathology; Biology; Medicine; Cell cycle; Oncology; Molecular biology; Cancer; Gene; Immunology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002031504,0.00009997435,0.0001305372,0.0004561285,0.0001380799,0.0003375919,0.0000773652,0.0001451694,0.0006426356],"category_scores_gemma":[0.0004970827,0.00008528052,0.00009854607,0.0004140991,0.0001797957,0.0001448349,0.0001457313,0.0002164805,0.0001442588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001466289,"about_ca_system_score_gemma":0.0001100315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008804938,"about_ca_topic_score_gemma":0.001187278,"domain_scores_codex":[0.9998891,0.0000151758,0.00001055861,0.0000278076,0.00003280272,0.00002443114],"domain_scores_gemma":[0.9998444,0.00004719364,0.00005041485,0.00001319653,0.00002258563,0.00002226193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003701659,0.00003603394,0.8633894,0.00003323105,0.0000472926,0.000334878,0.0001678591,0.0002745848,0.1206673,0.00005392153,0.0001529745,0.0144723],"study_design_scores_gemma":[0.00000898459,0.0001353556,0.982069,0.00000321875,0.00003886245,0.001466951,0.0001588994,0.0006025765,0.01476702,0.00006385508,0.0006822612,0.000003111177],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990869,0.0003321845,0.0001904004,0.00001278236,0.000001038147,0.000002850226,0.00009863523,0.000005353397,0.0002699269],"genre_scores_gemma":[0.9994159,0.0001462992,0.0001815689,0.000006714345,0.000002237168,0.000003473421,0.0001321553,0.000001262545,0.0001104173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008804938,"threshold_uncertainty_score":0.00214982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01006944229659738,"score_gpt":0.2548551505031196,"score_spread":0.2447857082065223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}