{"id":"W2318815641","doi":"10.1167/iovs.12-9570","title":"A Novel Schlemm's Canal Scaffold Increases Outflow Facility in a Human Anterior Segment Perfusion Model","year":2012,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Schlemm's canal; Trabecular meshwork; Intraocular pressure; Outflow; Glaucoma; Ophthalmology; Perfusion; Scaffold; Anatomy; Medicine; Ex vivo; Biomedical engineering; In vivo; Geology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001100521,0.0002823455,0.0004401995,0.000353679,0.0003833411,0.00002604764,0.0003728147,0.000135694,0.0001365062],"category_scores_gemma":[0.0006947748,0.0002284718,0.00008817129,0.000825193,0.003778756,0.0004039541,0.0003950048,0.0003217426,0.00003220138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003247285,"about_ca_system_score_gemma":0.0006527542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004647892,"about_ca_topic_score_gemma":0.00009223676,"domain_scores_codex":[0.9973816,0.0001146724,0.0004040083,0.0006032548,0.000590436,0.0009059755],"domain_scores_gemma":[0.9985837,0.00005232202,0.0001300316,0.0003400986,0.0001630129,0.0007308768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004744018,0.0005106232,0.4429465,0.00001663288,0.000004692462,0.00004082848,0.0007734905,0.00001014876,0.5555372,0.00004347613,0.00001083013,0.00005817874],"study_design_scores_gemma":[0.001037127,0.0007219021,0.9149227,0.0001971711,0.0000315807,0.000716414,0.0008201115,0.006050991,0.07489705,0.0003317333,0.000004879334,0.0002683987],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976309,0.0001439552,0.00001652491,0.0005267652,0.0001023336,0.0005028425,0.0000200616,0.00003305506,0.001023547],"genre_scores_gemma":[0.9974601,0.000002781597,0.001847984,0.0004043313,0.00003882606,0.00004901915,0.00001373847,0.00001076588,0.0001724409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4806401,"threshold_uncertainty_score":0.9989324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0472111986909611,"score_gpt":0.3449193758417586,"score_spread":0.2977081771507976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}