{"id":"W2318840660","doi":"10.1016/s0735-1097(16)32188-x","title":"EARLY ACTIVATION OF GROWTH PATHWAYS IN MITRAL LEAFLETS EXPOSED TO AORTIC REGURGITATION: ACTIVE MECHANISM TO PREVENT FUNCTIONAL MITRAL REGURGITATION IN THE DILATED VENTRICLE","year":2016,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Cardiac Valve Diseases and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Medicine; Functional mitral regurgitation; Cardiology; Ventricle; Internal medicine; Mitral regurgitation; Regurgitation (circulation); Left Ventricles; Mechanism (biology); Mitral valve; Heart failure; Ejection fraction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002711795,0.0003084166,0.0003813023,0.0002243055,0.0002122293,0.0005511399,0.0002116683,0.0003886655,0.001999222],"category_scores_gemma":[0.0002594557,0.0001399162,0.0003694126,0.00006890991,0.0002982307,0.0002862195,0.0003173536,0.001364821,0.0003214445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001911619,"about_ca_system_score_gemma":0.0003712046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001504196,"about_ca_topic_score_gemma":0.0002778137,"domain_scores_codex":[0.9998747,0.00002238624,0.00000643732,0.00002347363,0.00002545376,0.0000474653],"domain_scores_gemma":[0.9998679,0.00001406716,0.00002880555,0.00001086613,0.00001937144,0.00005884206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002092251,0.0005901782,0.002720542,0.000302065,0.0000324062,0.0003775117,0.0001086479,0.0001017147,0.9677328,0.0009138223,0.0005627559,0.0244654],"study_design_scores_gemma":[0.001869023,0.01349504,0.1846472,0.0003629183,0.0004371652,0.002337614,0.001164657,0.003328511,0.7660328,0.003713134,0.02255612,0.00005594023],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793531,0.01115679,0.004892436,0.00115863,0.0004886751,0.0001020207,0.0001915367,0.0001139897,0.002542785],"genre_scores_gemma":[0.9903046,0.00426666,0.002138698,0.0002394297,0.0001546073,0.00008734306,0.0001854094,0.0000175829,0.002605551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001999222,"threshold_uncertainty_score":0.006688058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01651388188873801,"score_gpt":0.2802263149940388,"score_spread":0.2637124331053008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}