{"id":"W2318915998","doi":"10.1515/hc.2002.8.6.521","title":"SYNTHESIS OF NOVEL THIAZOLE-CONTAINING BIS-1-CHLOROMETHYL-5-HYDROXY-1,2-DIHYDRO-3H-BENZ[e]INDOLE(seco-CBI)-POLYAMIDE CONJUGATES AS ANTICANCER AGENTS","year":2002,"lang":"en","type":"article","venue":"Heterocyclic Communications","topic":"Synthesis and properties of polymers","field":"Materials Science","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Thiazole; Indole test; Conjugate; Polyamide; Combinatorial chemistry; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005822218,0.0003994622,0.0007108017,0.0002691071,0.0006657228,0.0001551612,0.002473007,0.0001857515,0.004780411],"category_scores_gemma":[0.0006693597,0.0003721717,0.0002761224,0.0003284835,0.0007733327,0.000469395,0.0007879041,0.0003014152,0.0007170829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001082872,"about_ca_system_score_gemma":0.00004435506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001741533,"about_ca_topic_score_gemma":0.0002243885,"domain_scores_codex":[0.9969136,0.0003449385,0.001033302,0.0005270462,0.0005200428,0.0006611416],"domain_scores_gemma":[0.9946209,0.001580267,0.0005572101,0.002893256,0.0001200795,0.0002283297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006320654,0.0007590342,0.001334993,0.00007697651,0.0001431944,0.000002225047,0.002267339,0.00008973933,0.9806132,0.001106202,0.000605375,0.01293855],"study_design_scores_gemma":[0.0009078169,0.000159009,0.001453636,0.0004798169,0.0001831579,0.00003085975,0.001153129,0.007869941,0.9687428,0.0001286293,0.01817279,0.0007183795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9646262,0.004605764,0.0001074444,0.002318473,0.0003100415,0.0004200126,0.0001436758,0.0002019113,0.02726648],"genre_scores_gemma":[0.9936799,0.001970118,0.002856781,0.000640664,0.00006826143,0.0002352618,0.00001275236,0.0000702317,0.0004659623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02905377,"threshold_uncertainty_score":0.999873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0765708853585118,"score_gpt":0.297247084643923,"score_spread":0.2206761992854112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}