{"id":"W2319302126","doi":"10.1021/bm101080p","title":"Synthesis and Characterization of Carboxylic Acid Conjugated, Hydrophobically Derivatized, Hyperbranched Polyglycerols as Nanoparticulate Drug Carriers for Cisplatin","year":2010,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Dendrimers and Hyperbranched Polymers","field":"Materials Science","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Centre for Drug Research and Development","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Ethylene glycol; Carboxylate; Cisplatin; Zeta potential; Conjugated system; Potentiometric titration; Fourier transform infrared spectroscopy; Biocompatibility; Polymer chemistry; Nuclear chemistry; Polymer; Drug delivery; Stereochemistry; Combinatorial chemistry; Nanoparticle; Organic chemistry; Materials science; Nanotechnology; Chemical engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002468489,0.0002672332,0.0004354912,0.00009974881,0.0001741894,0.0001028941,0.0002415503,0.000153856,0.0002515099],"category_scores_gemma":[0.0001767818,0.0002437322,0.0001084649,0.0001663882,0.0003907652,0.00016126,0.00006872021,0.00007934887,0.00002541205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001127597,"about_ca_system_score_gemma":0.00008427287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001482651,"about_ca_topic_score_gemma":0.0000370543,"domain_scores_codex":[0.9983839,0.00006706887,0.0004501638,0.0004589001,0.0002323111,0.0004076261],"domain_scores_gemma":[0.9989957,0.00009160592,0.0002617259,0.0003454589,0.0001027499,0.0002027659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001559683,0.00005049994,0.0001507203,0.00006582388,0.00003433977,0.000008054082,0.0005514874,2.818145e-7,0.9972068,0.0004687536,0.00001525482,0.001292003],"study_design_scores_gemma":[0.0008360302,0.00008312781,0.001290554,0.00003560288,0.00009587863,0.0000282932,0.00004841487,0.0001340147,0.9964718,0.00008070438,0.0005990338,0.0002965026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997755,0.0001476714,0.0001088604,0.0003922194,0.0005554931,0.0004984733,0.0002261363,0.000075549,0.0002406202],"genre_scores_gemma":[0.9979445,0.00001644718,0.001586296,0.0001252976,0.0000660912,0.0001156547,0.00003646229,0.00004230743,0.00006696011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001477436,"threshold_uncertainty_score":0.9939108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005701193947049766,"score_gpt":0.2221100121132772,"score_spread":0.2164088181662274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}