{"id":"W2319730851","doi":"10.1016/j.cjca.2014.07.619","title":"MINICIRCLE DNA DEMONSTRATES IMPROVED TRANSFECTION EFFICIENCY AND LONGEVITY OVER CONVENTIONAL PLASMID BY ULTRASOUND-MEDIATED GENE DELIVERY","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Minicircle; Plasmid; Transfection; Microbubbles; Molecular biology; Gene delivery; Green fluorescent protein; DNA; Biology; Cationic liposome; Genetic enhancement; Cell biology; Gene; Medicine; Biochemistry; Ultrasound","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000345002,0.0003410584,0.0002753185,0.0002656241,0.0001706753,0.0004933263,0.0003633423,0.00051557,0.00141513],"category_scores_gemma":[0.0002798642,0.0002200394,0.0002326946,0.0002094972,0.0002900641,0.0003617671,0.0002346382,0.0005868854,0.0005534395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003440255,"about_ca_system_score_gemma":0.0002682078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008504352,"about_ca_topic_score_gemma":0.001169904,"domain_scores_codex":[0.9998031,0.00002335245,0.00001891279,0.00004864442,0.00007112384,0.00003483104],"domain_scores_gemma":[0.9998009,0.00004587288,0.00006279253,0.00002360654,0.00003598689,0.0000309202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003209295,0.000008285188,0.0000305618,0.00001272758,0.000001645471,0.00001701494,0.00001274268,0.00002025214,0.9985439,0.0001047504,0.00003825902,0.001177843],"study_design_scores_gemma":[0.000004719509,0.00008276014,0.0003599745,0.000001272982,0.000007493598,0.0000770907,0.000003239109,0.000208583,0.9977878,0.00001382334,0.001449147,0.000003999288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9685912,0.002359227,0.02471466,0.0003345354,0.000107256,0.00004786741,0.0003289661,0.0006781801,0.002837999],"genre_scores_gemma":[0.9762689,0.001018415,0.01178128,0.00007407877,0.00002375833,0.00004443647,0.0007080307,0.000146678,0.009934498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00141513,"threshold_uncertainty_score":0.004734099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003641145970973688,"score_gpt":0.1688594033915515,"score_spread":0.1652182574205778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}