{"id":"W2319927758","doi":"10.1371/journal.pone.0151837","title":"TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada","keywords":"T-cell receptor; Biology; Haematopoiesis; GTPase; Cell biology; STAT5; Immune system; Transgene; Signal transduction; Small GTPase; Phenotype; Molecular biology; Stem cell; Gene; T cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100322,0.0006537972,0.0002226582,0.0006342077,0.000165679,0.0003622323,0.0002692821,0.000671963,0.002678689],"category_scores_gemma":[0.0001564989,0.0002232488,0.0002345062,0.0002561143,0.0005771544,0.0002732096,0.0002697825,0.0007806237,0.0005653212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002083415,"about_ca_system_score_gemma":0.0001619856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002658501,"about_ca_topic_score_gemma":0.000343998,"domain_scores_codex":[0.999686,0.00004298074,0.00003147163,0.00006544661,0.00008029714,0.00009385843],"domain_scores_gemma":[0.9996628,0.00003155385,0.0001289051,0.00002311386,0.00001024302,0.0001434159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002121544,0.00002021745,0.0003157837,0.00001407067,0.000003319898,0.0001998154,0.000009661329,0.00003069026,0.9987822,0.00008096765,0.00001811715,0.0003129467],"study_design_scores_gemma":[0.00008041487,0.0004907585,0.03446294,0.00001413283,0.0000581508,0.00270481,0.0001320328,0.001371148,0.9585747,0.0002581003,0.001841063,0.00001168812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978236,0.0002603724,0.0006911625,0.00003893654,0.00001636682,0.000008149773,0.0003536512,0.00007000287,0.000737783],"genre_scores_gemma":[0.9973541,0.0001891014,0.0004761341,0.00002988984,0.000007543281,0.00001734871,0.0005200448,0.00002511015,0.001380745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002678689,"threshold_uncertainty_score":0.008961141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03059394837358593,"score_gpt":0.2044448782204426,"score_spread":0.1738509298468567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}