{"id":"W2320121910","doi":"10.1021/jf500983n","title":"Potential of a Renin Inhibitory Peptide from the Red Seaweed <i>Palmaria palmata</i> as a Functional Food Ingredient Following Confirmation and Characterization of a Hypotensive Effect in Spontaneously Hypertensive Rats","year":2014,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Marine Institute; European Cooperation in Science and Technology","keywords":"Hydrolysate; Captopril; Chemistry; Dipeptide; Peptide; Renin–angiotensin system; Blood pressure; Pharmacology; Papain; Functional food; In vivo; Ingredient; Whey protein; Internal medicine; Food science; Biochemistry; Enzyme; Medicine; Hydrolysis; Biology; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001052101,0.0003654132,0.0002038736,0.0001303814,0.0001010185,0.0002341633,0.0001079692,0.0001542505,0.0006732752],"category_scores_gemma":[0.0001140821,0.00008357163,0.0002691064,0.00008748464,0.000129347,0.0001810248,0.0001144405,0.0003271973,0.0001471479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001310196,"about_ca_system_score_gemma":0.0001086483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004261954,"about_ca_topic_score_gemma":0.0004670611,"domain_scores_codex":[0.9999459,0.000007674175,0.000004006929,0.00001507341,0.00001559824,0.00001168181],"domain_scores_gemma":[0.9998828,0.00001317762,0.00005093461,0.000009336642,0.00001513951,0.00002859365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002861811,0.00001945441,0.0002596627,0.00002644826,0.00000554217,0.00003221254,0.000005446353,0.00002624226,0.9981005,0.00000912297,0.000003726462,0.001225516],"study_design_scores_gemma":[0.000008670523,0.0008466324,0.005946147,0.000003253109,0.00002257593,0.0001693267,0.00001996347,0.0001888548,0.9922683,0.00001123929,0.0005116144,0.000003425276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974341,0.0005580424,0.001469094,0.00003536444,0.000008896943,0.00001104959,0.0001234542,0.00002251484,0.0003374793],"genre_scores_gemma":[0.9953676,0.0004797369,0.002615872,0.00003538652,0.000006866993,0.00001197289,0.0002383976,0.00001183909,0.001232275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006732752,"threshold_uncertainty_score":0.002252281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003671886121196558,"score_gpt":0.1663929750617191,"score_spread":0.1627210889405225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}