{"id":"W2320121910","doi":"10.1021/jf500983n","title":"Potential of a Renin Inhibitory Peptide from the Red Seaweed <i>Palmaria palmata</i> as a Functional Food Ingredient Following Confirmation and Characterization of a Hypotensive Effect in Spontaneously Hypertensive Rats","year":2014,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Marine Institute; European Cooperation in Science and Technology","keywords":"Hydrolysate; Captopril; Chemistry; Dipeptide; Peptide; Renin–angiotensin system; Blood pressure; Pharmacology; Papain; Functional food; In vivo; Ingredient; Whey protein; Internal medicine; Food science; Biochemistry; Enzyme; Medicine; Hydrolysis; Biology; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001960618,0.0001443062,0.0003058665,0.00001741771,0.00004803358,0.00001812289,0.00007084895,0.0001268668,0.00000186548],"category_scores_gemma":[0.0001624731,0.00008249104,0.0001378134,0.00006168964,0.00006630563,0.00001828242,0.00005900022,0.0001314411,6.705801e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001095178,"about_ca_system_score_gemma":0.0000250316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000256349,"about_ca_topic_score_gemma":0.00001091527,"domain_scores_codex":[0.9990845,0.00008138082,0.0003893471,0.0001574936,0.0001879776,0.00009924314],"domain_scores_gemma":[0.9990231,0.00005015906,0.0005431757,0.00007609669,0.0002558629,0.00005156457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004080316,0.00003282182,0.001546923,0.00003976816,0.0002081693,0.000003597787,0.00009943054,0.00001460185,0.9971815,0.000001111131,0.00003254957,0.0004314533],"study_design_scores_gemma":[0.00103982,0.0009087231,0.1330965,0.0001693403,0.0001067422,0.0002403359,0.0002661455,0.00001906765,0.8639932,0.00002828037,0.00003360584,0.00009821296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989978,0.0005186407,0.0000235559,0.0002154492,0.00006944445,0.0001204442,0.00002313387,0.000001591782,0.0000299043],"genre_scores_gemma":[0.9994276,0.0000801544,0.0000405926,0.00004767508,0.000270849,0.000003875527,0.0001070753,0.000004959517,0.00001724405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1331883,"threshold_uncertainty_score":0.3363887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003671886121196558,"score_gpt":0.1663929750617191,"score_spread":0.1627210889405225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}