{"id":"W2320174567","doi":"10.1385/endo:26:3:219","title":"Targeting Gonadotropin Receptor Genes: Reproductive Biology, Aging, and Related Health Implications","year":2005,"lang":"en","type":"review","venue":"Endocrine","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Endocrinology; Internal medicine; Knockout mouse; Gene knockout; Testosterone (patch); Estrogen; Null allele; Gonadotropin; Spermatogenesis; Estrogen receptor; Sexual maturity; Follicle-stimulating hormone receptor; Hormone; Receptor; Fertility; Phenotype; Reproductive biology; Gene; Luteinizing hormone; Follicle-stimulating hormone; Medicine; Genetics; Population; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002227012,0.0004194436,0.0008075694,0.0001065463,0.0001784062,0.00001821684,0.0002170278,0.0002959663,0.00003128964],"category_scores_gemma":[0.0001237043,0.0003487208,0.000231482,0.000196636,0.0001386286,0.000003653127,0.0002267067,0.0004559037,0.00005838378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006500314,"about_ca_system_score_gemma":0.0002424662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003602455,"about_ca_topic_score_gemma":0.000001405867,"domain_scores_codex":[0.9976061,0.0003101619,0.0005920435,0.0009761697,0.00005295605,0.0004625632],"domain_scores_gemma":[0.9987382,0.00002802756,0.0004160308,0.0006059934,0.00005007811,0.000161669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004255113,0.00004484464,0.00001328482,0.00076863,0.0003428114,0.000002373337,0.00002260007,0.000001618027,0.001949225,0.0001975433,0.00620345,0.9904494],"study_design_scores_gemma":[0.0002082514,0.0001960923,0.000003355278,0.0004983951,0.0001138859,0.0002711273,0.000008622684,7.933953e-7,0.0001937973,0.0000253549,0.9981509,0.000329453],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001225596,0.9977184,0.00004059781,0.0005565207,0.0002909148,0.0007944424,0.0001119062,0.00005339791,0.000311244],"genre_scores_gemma":[0.00005478504,0.992734,0.001144632,0.00007018211,0.0008814143,0.000132817,0.003288048,0.0000801817,0.001613994],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9919474,"threshold_uncertainty_score":0.9998965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01790182116873638,"score_gpt":0.3446601381847685,"score_spread":0.3267583170160321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}