{"id":"W2320174567","doi":"10.1385/endo:26:3:219","title":"Targeting Gonadotropin Receptor Genes: Reproductive Biology, Aging, and Related Health Implications","year":2005,"lang":"en","type":"review","venue":"Endocrine","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Endocrinology; Internal medicine; Knockout mouse; Gene knockout; Testosterone (patch); Estrogen; Null allele; Gonadotropin; Spermatogenesis; Estrogen receptor; Sexual maturity; Follicle-stimulating hormone receptor; Hormone; Receptor; Fertility; Phenotype; Reproductive biology; Gene; Luteinizing hormone; Follicle-stimulating hormone; Medicine; Genetics; Population; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007912382,0.001117585,0.001704703,0.001312599,0.0002819639,0.0009575922,0.001422326,0.001495496,0.003344563],"category_scores_gemma":[0.0007812927,0.0002879825,0.0003470338,0.001746292,0.0007496033,0.00116593,0.0004883087,0.0018905,0.002612105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008088197,"about_ca_system_score_gemma":0.0009398184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001406602,"about_ca_topic_score_gemma":0.003159825,"domain_scores_codex":[0.9998484,0.00001700899,0.00001638689,0.00003366248,0.00006813659,0.00001643898],"domain_scores_gemma":[0.9996153,0.0001666372,0.00004323702,0.00001478234,0.0001119593,0.00004793174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001341978,0.00007156456,0.0002207493,0.005735633,0.00006215314,0.0004376288,0.00004423103,0.0005112232,0.007636718,0.004532412,0.04497805,0.9356356],"study_design_scores_gemma":[0.00003415314,0.00006443417,0.0006591103,0.0008771253,0.00008973636,0.001408436,0.00006633242,0.00008869269,0.001632427,0.001947329,0.9931142,0.00001819081],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001975589,0.9969879,0.0005387455,0.0005065009,0.0003898985,0.00000490822,0.00002664206,0.00001819053,0.001329668],"genre_scores_gemma":[0.0007924463,0.9967451,0.0005093305,0.0003528827,0.0002105018,0.000008829722,0.00003667267,0.000002441076,0.001341816],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003344563,"threshold_uncertainty_score":0.01118869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01790182116873638,"score_gpt":0.3446601381847685,"score_spread":0.3267583170160321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}