{"id":"W2320236108","doi":"10.1021/jp305077k","title":"Multifaceted Substrate Capture Scheme of a Rhomboid Protease","year":2012,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Rhomboid; Scheme (mathematics); Substrate (aquarium); Protease; Computer science; Chemistry; Biology; Proteases; Mathematics; Biochemistry; Ecology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001532317,0.0003092696,0.000428443,0.0002576665,0.0006927582,0.0007661388,0.0006986035,0.0007023086,0.003138099],"category_scores_gemma":[0.0002745908,0.000271375,0.0003625331,0.0001640851,0.000563706,0.0007967842,0.0005505153,0.0004379741,0.0002475178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006944928,"about_ca_system_score_gemma":0.0004639443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001676312,"about_ca_topic_score_gemma":0.0009757873,"domain_scores_codex":[0.9999169,0.0000109647,0.000004999445,0.00001644792,0.0000250274,0.00002562992],"domain_scores_gemma":[0.9998941,0.00001874361,0.00001303653,0.0000245663,0.0000140011,0.00003561439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009335571,0.0002490639,0.007526282,0.0002215318,0.0001160617,0.001898816,0.0004406923,0.4381054,0.4175485,0.1138841,0.001005679,0.01807029],"study_design_scores_gemma":[0.00007060036,0.0001332092,0.001537228,0.000006802405,0.00001946289,0.0001462783,0.00005778731,0.9605349,0.02898547,0.007472927,0.0009995122,0.00003578695],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738355,0.0002734522,0.01939999,0.0001949281,0.00002793423,0.00003378048,0.00009936222,0.0002326116,0.005902434],"genre_scores_gemma":[0.9940758,0.0001218013,0.004867198,0.00002141425,0.000003044916,0.00002051336,0.00005885997,0.00001338394,0.0008179628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003138099,"threshold_uncertainty_score":0.01049799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353401651354803,"score_gpt":0.2804335639251888,"score_spread":0.2668995474116407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}