{"id":"W2320340716","doi":"10.1097/00007890-200004271-00720","title":"ABSENCE OF MHC CLASS I ON TRANSPLANTED NOD ISLETS PREVENTS AUTOIMMUNE INJURY AND CAUSES INFILTRATING CD4+ T CELLS TO PRODUCE TH2-LIKE CYTOKINES IN DIABETIC NOD MICE.","year":2000,"lang":"en","type":"article","venue":"Transplantation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre","funders":"","keywords":"Nod; NOD mice; Immunology; Major histocompatibility complex; Medicine; MHC class II; Autoimmunity; Autoimmune diabetes; Islet; MHC class I; Diabetes mellitus; Biology; Immune system; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001690786,0.0002985462,0.0002495916,0.0003905488,0.0001960284,0.0003443706,0.0003775702,0.0003170505,0.00558697],"category_scores_gemma":[0.000191382,0.0001459904,0.0001222702,0.0002366576,0.000220496,0.0002332475,0.0001704968,0.0007569113,0.001788041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001809296,"about_ca_system_score_gemma":0.0002822331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002502213,"about_ca_topic_score_gemma":0.0004797841,"domain_scores_codex":[0.9998289,0.00001836974,0.00001591987,0.00003856871,0.00005695016,0.00004119066],"domain_scores_gemma":[0.9997438,0.00001548273,0.00008004434,0.00002877757,0.00001142675,0.0001204968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009376591,0.0001928266,0.0007231209,0.00005535191,0.000006933663,0.0001511865,0.00001615784,0.00006139157,0.98809,0.0002682932,0.000581381,0.008915623],"study_design_scores_gemma":[0.0002913035,0.001703056,0.01777314,0.00003996192,0.00006049148,0.001612035,0.000112085,0.0004957003,0.9652254,0.0004200691,0.01225016,0.00001651542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832424,0.004625943,0.00231754,0.000545244,0.0003186364,0.00002838651,0.001245258,0.0003995838,0.007277135],"genre_scores_gemma":[0.9758405,0.003289775,0.002527266,0.0001755841,0.0001152858,0.00005538229,0.001601302,0.0001447886,0.01625014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00558697,"threshold_uncertainty_score":0.01869029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004677691427153645,"score_gpt":0.2233582689703789,"score_spread":0.2186805775432253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}