{"id":"W2320448647","doi":"10.1097/qad.0000000000000381","title":"Soluble Toll-like receptor 2 is significantly elevated in HIV-1 infected breast milk and inhibits HIV-1 induced cellular activation, inflammation and infection","year":2014,"lang":"en","type":"article","venue":"AIDS","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Ministerio de Economía y Competitividad","keywords":"TLR2; Proinflammatory cytokine; Breast milk; Gp41; Immunology; Chemokine; Inflammation; Receptor; Biology; Toll-like receptor; Innate immune system; Medicine; Immune system; Internal medicine; TLR4; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004882455,0.0002118025,0.0002666428,0.0003976435,0.0002070098,0.00004486993,0.00005782197,0.0004024008,0.0001851549],"category_scores_gemma":[0.0001665595,0.0002126379,0.00003108264,0.0003808699,0.000105083,0.0005160842,0.00006156319,0.0002989039,0.0002736779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005632359,"about_ca_system_score_gemma":0.00005071694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002585248,"about_ca_topic_score_gemma":0.00002780261,"domain_scores_codex":[0.9984973,0.0004134179,0.0004351823,0.0003190026,0.00005083628,0.0002842691],"domain_scores_gemma":[0.9992826,0.0001407894,0.0001895946,0.0002038889,0.0001561836,0.00002694394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002774299,0.00003492497,0.02089601,0.00002751367,0.0000437076,2.131666e-7,0.0009804489,0.000002534077,0.9621222,0.0003367891,0.0005745821,0.01470362],"study_design_scores_gemma":[0.00203124,0.0002686607,0.07146523,0.00008367901,0.00002264871,0.00001890256,0.00007615637,0.0001411054,0.9159521,0.0001028092,0.00959786,0.0002395548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997754,0.00007470557,0.0007719357,0.0004776097,0.0002687207,0.0003452147,0.000005771784,0.00009328293,0.000208809],"genre_scores_gemma":[0.9986029,0.00007068366,0.0000486791,0.00009679501,0.00006341605,0.00003232524,0.000392695,0.00002078693,0.0006717153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05056921,"threshold_uncertainty_score":0.8671123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007479409605612583,"score_gpt":0.2036631250640648,"score_spread":0.1961837154584522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}