{"id":"W2320475433","doi":"10.1021/mp200490b","title":"Diazo Transfer and Click Chemistry in the Solid Phase Syntheses of Lysine-Based Glycodendrimers as Antagonists against <i>Escherichia coli</i> FimH","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmaceutics","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Chemistry; Escherichia coli; Click chemistry; Lectin; Mannose; Triazole; Adhesion; Stereochemistry; Biochemistry; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002363559,0.0005098236,0.0002168203,0.0001589552,0.0001192466,0.0002194471,0.0003089919,0.000377857,0.0008259888],"category_scores_gemma":[0.0001628589,0.0002071589,0.0003273439,0.0001849483,0.0002823042,0.0003623338,0.0002501455,0.0003965689,0.0004997565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003088945,"about_ca_system_score_gemma":0.0002475308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002516576,"about_ca_topic_score_gemma":0.0004989937,"domain_scores_codex":[0.9998679,0.0000238273,0.00001083733,0.0000282591,0.00003311584,0.00003594203],"domain_scores_gemma":[0.9999367,0.00001325456,0.00002258085,0.000009074492,0.000006956906,0.00001147108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001010376,0.00003907312,0.00004557328,0.00008240758,0.000008078535,0.0001463926,0.0000318766,0.0005206323,0.9938159,0.00107792,0.00009029071,0.00404085],"study_design_scores_gemma":[0.00002514993,0.0003014771,0.0002530249,0.000002831559,0.000009031536,0.000183301,0.000005451179,0.0006723411,0.9964244,0.00009661783,0.002017802,0.000008563143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9550682,0.002737853,0.0320852,0.0001924017,0.0001176799,0.0001735977,0.0002475383,0.0003052294,0.009072173],"genre_scores_gemma":[0.9787318,0.001318714,0.01591588,0.00006794906,0.00002517347,0.00007323911,0.0001535084,0.00003378743,0.003679989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008259888,"threshold_uncertainty_score":0.002763271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03844114873378503,"score_gpt":0.3091754794087291,"score_spread":0.2707343306749441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}