{"id":"W2320624220","doi":"10.1371/journal.ppat.1005481","title":"IL-22 Restrains Tapeworm-Mediated Protection against Experimental Colitis via Regulation of IL-25 Expression","year":2016,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Crohn's and Colitis Canada; Canadian Institutes of Health Research; Alberta Innovates; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Canadian Association of Gastroenterology","keywords":"Colitis; Hymenolepis diminuta; Immune system; Mesenteric lymph nodes; Immunology; Cytokine; Biology; Tumor necrosis factor alpha; Molecular biology; Chemistry; Helminths","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007264109,0.0003080119,0.0001776475,0.0002192384,0.0001008769,0.0002247954,0.000123114,0.000155816,0.0008763795],"category_scores_gemma":[0.00006874353,0.0001037085,0.0001617172,0.00006957244,0.0002103794,0.0001073692,0.000115292,0.0004983642,0.0002505281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001156332,"about_ca_system_score_gemma":0.0001069107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003134018,"about_ca_topic_score_gemma":0.0007171814,"domain_scores_codex":[0.9999168,0.00001694312,0.000007538511,0.0000136803,0.0000172509,0.00002777113],"domain_scores_gemma":[0.9998927,0.000008259,0.00003514448,0.00000929982,0.000008768173,0.00004570312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002104136,0.00004953268,0.0002839085,0.00003316687,0.000003256238,0.00005921194,0.00001382935,0.00003850684,0.9982269,0.00002124492,0.00002429089,0.0010358],"study_design_scores_gemma":[0.00005170153,0.002275817,0.02044833,0.00002283972,0.00003660556,0.0003458423,0.00009616176,0.0007401257,0.9734004,0.00006502753,0.002508934,0.000008156049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970766,0.001072369,0.0005825218,0.00005167843,0.00002206547,0.00002029903,0.0001576753,0.00008144788,0.000935362],"genre_scores_gemma":[0.996684,0.0007786259,0.0005830512,0.00004026106,0.00001233031,0.00002598042,0.0002095361,0.000009469366,0.001656682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008763795,"threshold_uncertainty_score":0.002931714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02061889076701436,"score_gpt":0.2572113187708632,"score_spread":0.2365924280038488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}