{"id":"W2320627933","doi":"10.2147/ov.s66217","title":"High-throughput screening to enhance oncolytic virus immunotherapy","year":2016,"lang":"en","type":"review","venue":"Oncolytic Virotherapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"Government of Canada; Terry Fox Research Institute; Ontario Institute for Cancer Research","keywords":"Oncolytic virus; Vaccinia; Herpes simplex virus; Virus; Computational biology; Disease; Biology; CRISPR; Virology; Medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007488101,0.001043861,0.001287355,0.002511093,0.0002616272,0.00115239,0.0008752346,0.001174739,0.003250892],"category_scores_gemma":[0.0005448929,0.000494209,0.0008585757,0.001619658,0.0004365332,0.001335545,0.0007444222,0.001726321,0.002769198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008737748,"about_ca_system_score_gemma":0.0006101153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005446458,"about_ca_topic_score_gemma":0.001116422,"domain_scores_codex":[0.9995381,0.00007331008,0.0000295418,0.00006493877,0.0002462278,0.00004800063],"domain_scores_gemma":[0.9997887,0.00008694724,0.00002973394,0.00001306357,0.00006408613,0.00001755041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001305672,0.0003887544,0.0004183133,0.01778471,0.000225252,0.0005351048,0.0001379393,0.002358172,0.1127117,0.01378655,0.0290114,0.8225116],"study_design_scores_gemma":[0.00004148397,0.0003207659,0.001045771,0.0009243706,0.0001566307,0.001682487,0.00005674167,0.001231203,0.06614257,0.002478821,0.9258538,0.00006536603],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002998845,0.9714481,0.011553,0.0004865116,0.0004402866,0.0001493751,0.0001912078,0.0002269025,0.01250576],"genre_scores_gemma":[0.01592922,0.9684475,0.006972744,0.000502335,0.0001546888,0.0001253715,0.0002963819,0.00003313833,0.007538659],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003250892,"threshold_uncertainty_score":0.01087534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03293868116363912,"score_gpt":0.3924652041768385,"score_spread":0.3595265230131994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}