{"id":"W2320670917","doi":"10.1101/pdb.prot080234","title":"High-Throughput RNAi Screening for Germline Apoptosis Genes in <i>Caenorhabditis elegans</i>","year":2014,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Caenorhabditis elegans; RNA interference; Germline; Biology; Gene; Acridine orange; Phenotype; Mutant; Apoptosis; Genetics; Cell biology; Transgene; Genome; Computational biology; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005401333,0.0007543571,0.0004680271,0.0008542072,0.0007216134,0.0005273033,0.0009181682,0.0003868258,0.002233234],"category_scores_gemma":[0.0002228522,0.000530421,0.0006585942,0.0003497812,0.0003995622,0.0002783545,0.0004942465,0.0008506755,0.001141352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008048295,"about_ca_system_score_gemma":0.0006268146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003855987,"about_ca_topic_score_gemma":0.01644624,"domain_scores_codex":[0.9994966,0.00004012027,0.00005895651,0.00009543485,0.0002537431,0.00005509325],"domain_scores_gemma":[0.9997221,0.00005972425,0.0000742819,0.00004832956,0.00005727084,0.00003834664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001867397,0.00001929812,0.000104619,0.00004519022,0.000006887345,0.00003169841,0.00001017215,0.00008445777,0.9979615,0.0001010711,0.0002509262,0.001365519],"study_design_scores_gemma":[0.00001902497,0.00009592891,0.002265067,0.00001343966,0.00002871759,0.0001469943,0.00001099232,0.000747546,0.991841,0.00004060538,0.004776584,0.00001402399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.8013378,0.002894016,0.1464509,0.0004633733,0.0001894941,0.002806524,0.01997378,0.006375024,0.01950895],"genre_scores_gemma":[0.7142411,0.00607809,0.211386,0.0005465415,0.00004923341,0.003417576,0.02103207,0.001506986,0.04174244],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.003855987,"threshold_uncertainty_score":0.007667065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01566498160861234,"score_gpt":0.2616488053469076,"score_spread":0.2459838237382952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}