{"id":"W2320894692","doi":"10.1021/om500479q","title":"Iron Catalysts Containing Amine(imine)diphosphine P-NH-N-P Ligands Catalyze both the Asymmetric Hydrogenation and Asymmetric Transfer Hydrogenation of Ketones","year":2014,"lang":"en","type":"article","venue":"Organometallics","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Medicinal chemistry; Catalysis; Acetophenone; Transfer hydrogenation; Hydride; Imine; Heterolysis; Amine gas treating; Organic chemistry; Hydrogen; Ruthenium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00112351,0.0004976606,0.0007232121,0.001197421,0.0003160556,0.0001121004,0.0006049623,0.0003143864,0.0001821465],"category_scores_gemma":[0.001019746,0.0004118111,0.0002847013,0.005127443,0.0002249705,0.0003708464,0.0001436395,0.0003389574,0.00003959501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001651615,"about_ca_system_score_gemma":0.00008010791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002314698,"about_ca_topic_score_gemma":0.0000679983,"domain_scores_codex":[0.9967052,0.00006031737,0.001017402,0.0007153874,0.0009968472,0.000504801],"domain_scores_gemma":[0.9976171,0.0006232493,0.0004148676,0.0008164915,0.0002862678,0.0002420091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003127588,0.001843011,0.04727877,0.001472436,0.002499748,0.0000268332,0.005502994,0.0009134494,0.324148,0.01932559,0.0004596581,0.5962167],"study_design_scores_gemma":[0.00260652,0.0001850598,0.005192477,0.00004569988,0.000972298,0.00007453733,0.0005947028,0.01724434,0.9611691,0.0002323244,0.01075306,0.0009298486],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811931,0.002532038,0.003358965,0.0004367131,0.0001127736,0.0002493051,0.00006883623,0.0001499029,0.01189832],"genre_scores_gemma":[0.9972104,0.0005514404,0.0001218288,0.0001580161,0.0001761949,0.00004377311,0.0006951065,0.00009770494,0.0009454841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6370211,"threshold_uncertainty_score":0.9998333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008235023675280808,"score_gpt":0.2115474088441724,"score_spread":0.2033123851688916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}