{"id":"W2320948155","doi":"10.1021/jo2008719","title":"Chiral Propargyl Alcohols via the Enantioselective Addition of Terminal Di- and Triynes to Aldehydes","year":2011,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University of Alberta","keywords":"Enantioselective synthesis; Propargyl; Alkynylation; Chemistry; Aryl; Silylation; Alkyl; Catalysis; Organic chemistry; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002076982,0.000656574,0.0002513698,0.000245812,0.0001358027,0.0002903089,0.0004391925,0.0002201729,0.002069654],"category_scores_gemma":[0.0001811229,0.000217922,0.0002442072,0.0001897835,0.0002098339,0.0003571247,0.0004000196,0.0008052905,0.001831401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002578822,"about_ca_system_score_gemma":0.0003053099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003757403,"about_ca_topic_score_gemma":0.001119112,"domain_scores_codex":[0.9998004,0.00002292962,0.00002286841,0.00002926923,0.00006450813,0.00006006664],"domain_scores_gemma":[0.9999231,0.000006998368,0.00001788238,0.0000164903,0.00001415484,0.00002135963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001023282,0.00004120593,0.0001040816,0.0001526209,0.00001153709,0.0007587189,0.00006188869,0.0003333887,0.9883679,0.001962289,0.0003027519,0.007801397],"study_design_scores_gemma":[0.00001161284,0.00009908745,0.0001750781,0.000005255431,0.000007687956,0.0003751497,0.00001113347,0.0002315301,0.993473,0.0001090855,0.005494191,0.00000718176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8524639,0.004017134,0.0751232,0.0005852188,0.0003938885,0.0003758894,0.001317593,0.00136504,0.06435808],"genre_scores_gemma":[0.9664683,0.003450221,0.01718502,0.0001403156,0.00004205646,0.00005828862,0.0006525779,0.0001040437,0.01189907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002069654,"threshold_uncertainty_score":0.006923676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02182463554285687,"score_gpt":0.2513865544026356,"score_spread":0.2295619188597788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}