{"id":"W2320984091","doi":"10.1158/1535-7163.targ-13-c225","title":"Abstract C225: IL1RAP as functionally relevant target for stem-cell directed therapy in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).","year":2013,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"","keywords":"Myeloid leukemia; Medicine; Stem cell; Myelodysplastic syndromes; CD34; Cancer research; Progenitor cell; clone (Java method); Internal medicine; Immunology; Biology; Bone marrow; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001184689,0.0002801562,0.0002595618,0.0001911688,0.0001325749,0.0002887127,0.0001956732,0.0003075516,0.001781331],"category_scores_gemma":[0.00006324994,0.00007084833,0.0001863608,0.0001627797,0.0001533429,0.0001051025,0.0001465566,0.0004878469,0.0004860988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002789448,"about_ca_system_score_gemma":0.000270959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003228013,"about_ca_topic_score_gemma":0.0005548769,"domain_scores_codex":[0.9999224,0.00001289963,0.000006329443,0.00001449214,0.00002466235,0.00001922819],"domain_scores_gemma":[0.9999592,0.000004411937,0.00001136421,0.00000383948,0.000007202472,0.00001405005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005047387,0.00007688238,0.0003908811,0.0001098602,0.0000132251,0.00007883015,0.00001356083,0.0001641196,0.9898896,0.000207586,0.0004053871,0.008145257],"study_design_scores_gemma":[0.0001729579,0.001917557,0.006548649,0.00002468859,0.0000979398,0.0009300337,0.00002497714,0.001317393,0.9728224,0.000114494,0.0160192,0.000009653148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825361,0.01085621,0.002037892,0.0003525142,0.0001696556,0.0001437162,0.001024307,0.0001355352,0.002744222],"genre_scores_gemma":[0.9899918,0.002664552,0.002591998,0.0002247559,0.00003817737,0.0001113996,0.00153596,0.0000211244,0.002820255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001781331,"threshold_uncertainty_score":0.005959213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02216449080055211,"score_gpt":0.2887105411447374,"score_spread":0.2665460503441853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}