{"id":"W2320984091","doi":"10.1158/1535-7163.targ-13-c225","title":"Abstract C225: IL1RAP as functionally relevant target for stem-cell directed therapy in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).","year":2013,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"","keywords":"Myeloid leukemia; Medicine; Stem cell; Myelodysplastic syndromes; CD34; Cancer research; Progenitor cell; clone (Java method); Internal medicine; Immunology; Biology; Bone marrow; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003021864,0.0004876064,0.000682839,0.0003128505,0.0001517078,0.0001427447,0.0002795237,0.0003547422,0.0005898635],"category_scores_gemma":[0.00002302717,0.0004438411,0.0001926206,0.0004935002,0.0002083754,0.0001842346,0.00008017213,0.0007055786,0.00008872568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001054508,"about_ca_system_score_gemma":0.001400664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001143654,"about_ca_topic_score_gemma":0.00007073732,"domain_scores_codex":[0.9969795,0.00009890542,0.0005824423,0.0007703764,0.0006880165,0.0008807495],"domain_scores_gemma":[0.9982191,0.0002994601,0.0001772446,0.0005575624,0.0004382509,0.0003083713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001898782,0.0003142144,0.006340803,0.0003963286,0.001684619,0.0003782819,0.0005703396,0.0002453563,0.8941091,0.0001026055,0.002006276,0.09195329],"study_design_scores_gemma":[0.05535462,0.008839925,0.2772216,0.001279973,0.00163101,0.0009280069,0.001203392,0.03136514,0.4062245,0.007225531,0.2046349,0.004091374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823254,0.01037362,0.0009530911,0.002525463,0.0002619433,0.002542041,0.00007708301,0.0001708485,0.0007705652],"genre_scores_gemma":[0.9786838,0.009196555,0.002516704,0.003892754,0.0001312091,0.001203241,0.0001161656,0.0002059311,0.004053607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4878846,"threshold_uncertainty_score":0.9998013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02216449080055211,"score_gpt":0.2887105411447374,"score_spread":0.2665460503441853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}