{"id":"W2321330838","doi":"10.1158/1538-7445.am2012-736","title":"Abstract 736: RTOG 0320:A phase III trial comparing whole brain radiation therapy (WBRT) and stereotactic radiosurgery (SRS) alone versus WBRT with temozolomide (TMZ) or erlotinib for non-small cell lung cancer (NSCLC) and 1-3 brain metastases","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University; Ottawa Hospital; McGill University","funders":"","keywords":"Medicine; Erlotinib; Radiosurgery; Lung cancer; Temozolomide; Internal medicine; Oncology; Clinical endpoint; Concomitant; Radiation therapy; Hazard ratio; Cancer; Randomized controlled trial; Confidence interval; Epidermal growth factor receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002584157,0.0003983178,0.0008928832,0.0003464585,0.0003948655,0.0001509736,0.000125078,0.0001214472,0.0003189829],"category_scores_gemma":[0.000247164,0.0002803572,0.0001252801,0.0004229508,0.0002370233,0.0003626181,0.00006321284,0.0004756262,0.000003586083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004398854,"about_ca_system_score_gemma":0.0008370131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001998314,"about_ca_topic_score_gemma":0.0005299909,"domain_scores_codex":[0.9968462,0.0003005742,0.0004986097,0.0006525315,0.0006243561,0.001077741],"domain_scores_gemma":[0.9954258,0.003077766,0.0002265074,0.0004303631,0.0002070752,0.0006324908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6681194,0.00370399,0.0387071,0.001838441,0.003755123,0.0002522664,0.004478407,0.00005085479,0.02929632,0.00004149448,0.05930931,0.1904473],"study_design_scores_gemma":[0.8475818,0.01022446,0.02316161,0.0009445896,0.001267465,0.0001066232,0.001930294,0.001216377,0.0347979,0.00001000225,0.07765128,0.001107624],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714193,0.0197125,0.0001009535,0.003202977,0.0004100234,0.004719122,0.0002756571,0.00003699028,0.0001224497],"genre_scores_gemma":[0.9932898,0.002134185,0.0004188039,0.0003433687,0.001077834,0.001670616,0.0002209735,0.00009561347,0.0007488342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1893396,"threshold_uncertainty_score":0.9999648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1388450034360342,"score_gpt":0.4321983631062408,"score_spread":0.2933533596702066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}