{"id":"W2321330838","doi":"10.1158/1538-7445.am2012-736","title":"Abstract 736: RTOG 0320:A phase III trial comparing whole brain radiation therapy (WBRT) and stereotactic radiosurgery (SRS) alone versus WBRT with temozolomide (TMZ) or erlotinib for non-small cell lung cancer (NSCLC) and 1-3 brain metastases","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University; Ottawa Hospital; McGill University","funders":"","keywords":"Medicine; Erlotinib; Radiosurgery; Lung cancer; Temozolomide; Internal medicine; Oncology; Clinical endpoint; Concomitant; Radiation therapy; Hazard ratio; Cancer; Randomized controlled trial; Confidence interval; Epidermal growth factor receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001874622,0.0020644,0.002396987,0.0005417924,0.0004450391,0.001034225,0.001392487,0.001482448,0.01072091],"category_scores_gemma":[0.001318911,0.0005885543,0.001937104,0.0007550249,0.000940157,0.0006163885,0.0003597577,0.003302671,0.002437058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009499708,"about_ca_system_score_gemma":0.002421725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001898412,"about_ca_topic_score_gemma":0.004291,"domain_scores_codex":[0.9993912,0.0003769505,0.00003664002,0.00007102305,0.00004302231,0.00008108682],"domain_scores_gemma":[0.9991834,0.0001766323,0.0001826558,0.00005244577,0.00005094906,0.0003539525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.947558,0.01299481,0.001165717,0.0005745473,0.001131581,0.00006454152,0.00006705869,0.0007326885,0.007681516,0.0001248342,0.003164256,0.02474049],"study_design_scores_gemma":[0.9019251,0.09266622,0.002160354,0.00002780031,0.0005755216,0.00006720471,0.00001732629,0.0005211749,0.001017907,0.0001207108,0.0008843848,0.00001630059],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813932,0.002617104,0.0007356405,0.0007565962,0.0002834279,0.005552242,0.004182707,0.0003884376,0.004090721],"genre_scores_gemma":[0.9706603,0.001936177,0.002640251,0.001587784,0.0003940747,0.008995075,0.005295014,0.0001109308,0.008380427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01072091,"threshold_uncertainty_score":0.03586501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1388450034360342,"score_gpt":0.4321983631062408,"score_spread":0.2933533596702066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}